Table 3. Interaction model estimates progression free survival (PFS) in high-grade and low-grade endometrial endometrioid cancer (EEC) patients.

Interaction between adjuvant therapy type and grade (high vs. low) was significant for PFS (p=0.04). The CHEMO+/− RAD had superior HR compared to RAD and OBS in the high grade patients; in low grade patients CHEMO +/− RAD was only superior to OBS, but not to RAD.

	HR	95% CI
High grade EEC
CHEMO +/− RAD vs. OBS	0.10	(0.03–0.32)
CHEMO +/− RAD vs. RAD	0.25	(0.09–0.71)
Low grade EEC
CHEMO +/− RAD vs. OBS	0.34	(0.14–0.82)
CHEMO +/− RAD vs. RAD	1.36	(0.57–3.28)

HR, hazard ratio. CI, confidence interval.