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. 2020 Jul 17;2020(7):CD005331. doi: 10.1002/14651858.CD005331.pub3

Summary of findings 3. Hypnosis compared with wait list.

Hypnosis compared with wait list for conversion disorder
Patient or population: people with conversion disorder according to DSM‐IV or ICD‐10 criteria
Settings: outpatient
Intervention: hypnosis
Comparison: wait list
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of participants
(studies) Certainty of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
Wait list Hypnosis
Reduction in physical signs (Severity of impairment)
Measured by the VRMC scale (higher is better)
Range: 1–7
End of treatment
The mean reduction in physical signs in the control group was 3.8 MD 2.10 higher
(1.34 higher to 2.86 higher)
49
(1 study) ⊕⊕⊝⊝
Lowa,b Hypnosis may have little effect on reduction in physical signs at end of treatment
Level of functioning No studies assessed this outcome
Quality of life No studies assessed this outcome
Adverse events No studies assessed this outcome
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; DSM‐IV:Diagnostic and Statistical Manual of Mental Disorders 4th Edition; ICD‐10:International Classification of Diseases, Tenth Revision; MD: mean difference; VRMC: Video Rating Scale for Motor Conversion Symptoms.
GRADE Working Group grades of evidence
High quality: further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: we are very uncertain about the estimate.

aDowngraded one level due to high risk of bias.
bDowngraded one level due to imprecision (based on 1 study with few patients).