Summary of findings 4. Behavioural therapy plus treatment as usual compared with treatment as usual.
| Behavioural therapy + TAU compared with TAU for conversion disorder | ||||||
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Patient or population: people with conversion disorder according to DSM‐IV or ICD‐10 criteria Settings: inpatient Intervention: behavioural therapy + TAU Comparison: TAU | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| TAU | Behavioural therapy + TAU | |||||
|
Reduction in physical signs Number of weekly seizures, as assessed by daily self‐reported treatment diary End of treatment |
The mean reduction in physical signs in the control group was 27.8 |
MD 21.40 lower (27.88 lower to 14.92 lower) |
— | 18 (1 study) |
Very lowa,b ⊕⊝⊝⊝ |
Behavioural therapy + TAU may have little effect on reduction in physical signs at end of treatment. |
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Reduction in physical signs (symptom severity) Measured by Clinical Global Impression scale (lower is better) Range: 1–7 End of treatment |
The mean reduction in physical signs in the control group was 4.48 |
MD 2.90 lower (3.41 lower to 2.39 lower) |
— | 90 (1 study) |
Very lowa,b ⊕⊝⊝⊝ |
Behavioural therapy + TAU may have little effect on reduction in physical signs at end of treatment. |
| Level of functioning | — | — | — | — | — | No studies assessed this outcome. |
| Quality of life | — | — | — | — | — | No studies assessed this outcome. |
| Adverse events | — | — | — | — | — | No studies assessed this outcome. |
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; DSM‐IV:Diagnostic and Statistical Manual of Mental Disorders 4th Edition; ICD‐10:International Classification of Diseases, Tenth Revision; MD: mean difference. | ||||||
| GRADE Working Group grades of evidence High quality: further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: we are very uncertain about the estimate. | ||||||
aDowngraded two levels due to high risk of bias. bDowngraded one level due to imprecision (data based on 1 study with few participants).