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. 2020 Jul 17;2020(7):CD005331. doi: 10.1002/14651858.CD005331.pub3

Summary of findings 7. Specialised cognitive behavioural therapy‐based physiotherapy compared with waitlist.

Specialised CBT‐based physiotherapy programme compared with wait list for conversion disorder
Patient or population: people with conversion disorder according to DSM‐IV or ICD‐10 criteria
Settings: inpatient
Intervention: specialised CBT‐based physiotherapy programme
Comparison: wait list
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of participants
(studies) Certainty of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
Wait list Specialised CBT‐based physiotherapy
Reduction in physical signs
End of treatment
No studies assessed this outcome.
Level of functioning
As measured by FIM (higher is better)
Range: 18–126
End of treatment
The mean level of functioning in the control group was 80.9 MD 9.20 higher
(6.06 higher to 12.34 higher)
118
(1 study) ⊕⊕⊝⊝
Lowa,b Specialised CBT‐based physiotherapy may slightly improve level of functioning at end of treatment.
Quality of life No studies assessed this outcome.
Adverse events No studies assessed this outcome.
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CBT: cognitive behavioural therapy; CI: confidence interval; DSM‐IV:Diagnostic and Statistical Manual of Mental Disorders 4th Edition; FIM: Functional Independence Measure Motor; ICD‐10:International Classification of Diseases, Tenth Revision; MD: mean difference.
GRADE Working Group grades of evidence
High quality: further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: we are very uncertain about the estimate.

aDowngraded one level due to high risk of bias.
bDowngraded one level due to imprecision (based on one study with few patients).