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. 2020 Jul 17;2020(7):CD005331. doi: 10.1002/14651858.CD005331.pub3

Summary of findings 11. Hypnosis compared with diazepam.

Hypnosis compared with diazepam for conversion disorder
Patient or population: people with conversion disorder according to DSM‐IV or ICD‐10 criteria
Settings: emergency unit
Intervention: hypnosis
Comparison: diazepam
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of participants
(studies) Certainty of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
Diazepam Hypnosis
Reduction in physical signs
Number with symptom freedom
End of treatment
Study population RR 0.69 (0.39 to 1.24) 40
(1 study) ⊕⊝⊝⊝
Very lowa,b Hypnosis may have no effect on physical signs at end of treatment.
650 per 1000 448 per 1000
(397 less to 156 more)
Level of functioning No studies assessed this outcome.
Quality of life No studies assessed this outcome.
Adverse events No studies assessed this outcome.
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; DSM‐IV:Diagnostic and Statistical Manual of Mental Disorders 4th Edition; ICD‐10:International Classification of Diseases, Tenth Revision; RR: risk ratio.
GRADE Working Group grades of evidence
High quality: further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: we are very uncertain about the estimate.

aDowngraded one level due to high risk of bias.
bDowngraded two levels due to imprecision (Wide confidence interval and based on one study with few patients).