Summary of findings 11. Hypnosis compared with diazepam.
Hypnosis compared with diazepam for conversion disorder | ||||||
Patient or population: people with conversion disorder according to DSM‐IV or ICD‐10 criteria Settings: emergency unit Intervention: hypnosis Comparison: diazepam | ||||||
Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
Assumed risk | Corresponding risk | |||||
Diazepam | Hypnosis | |||||
Reduction in physical signs Number with symptom freedom End of treatment |
Study population | RR 0.69 (0.39 to 1.24) | 40 (1 study) | ⊕⊝⊝⊝ Very lowa,b | Hypnosis may have no effect on physical signs at end of treatment. | |
650 per 1000 | 448 per 1000 (397 less to 156 more) | |||||
Level of functioning | — | — | — | — | — | No studies assessed this outcome. |
Quality of life | — | — | — | — | — | No studies assessed this outcome. |
Adverse events | — | — | — | — | — | No studies assessed this outcome. |
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval; DSM‐IV:Diagnostic and Statistical Manual of Mental Disorders 4th Edition; ICD‐10:International Classification of Diseases, Tenth Revision; RR: risk ratio. | ||||||
GRADE Working Group grades of evidence High quality: further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: we are very uncertain about the estimate. |
aDowngraded one level due to high risk of bias. bDowngraded two levels due to imprecision (Wide confidence interval and based on one study with few patients).