Drane 2016.

Study characteristics
Methods	Study design: randomised controlled trial Study grouping: parallel group Adequate power (evidence of power calculation): not adequate in power. Power analysis suggested a sample of ≥ 23 participants per group in order to detect a statistically significant difference in event frequency at 8 weeks. While we were unable to achieve this enrolment goal, our findings nevertheless achieved statistical significance. Allocation concealment method: none mentioned Blinding of outcome assessors: none mentioned Check of blinding: none mentioned Duration of study: July 2011 to May 2012 Randomisation method: simple randomisation (preset randomisation chart that was based on computer generation of random numbers).
Participants	Baseline characteristics Intervention n: 15 Age (mean): 34.1 (SD 9.5) years Sex (% woman): 86.67% Educational status: 13.9 (SD 3.1) years Control n: 12 Age (mean): 45.3 (SD 11.5) years Sex (% woman): 83.3% Educational status: 13.3 (SD 2.5) years Overall n: 27 Inclusion criteria: diagnosis of PNES based on recognised criteria. Exclusion criteria: epileptiform activity during an episode and semiology characterised by: 1. a definitive motor component (e.g. shaking or writhing of the torso or limbs, convulsive or rocking movements, head shaking) or 2. a discrete episode of unresponsiveness and 3. the clinical impression that the event could not be explained by another physiological cause (e.g. syncope, sleep disturbance). Severe cognitive impairment or active homicidal or suicidal ideation. Pretreatment: age was the only baseline variable to significantly differ between groups (standard practice 45.3 (SD 11.5) years; structured inpatient feedback 37.7 (SD 10.5) years, structured ongoing feedback 34.1 (SD 9.5) years).
Interventions	Intervention characteristics Intervention Description: structured ongoing feedback (scripted delivery of diagnosis, inpatient psychiatric consultation, educational handout material and 4 weekly follow‐up calls) Length of treatment: 5 weeks Longest follow‐up after end of treatment: 3 weeks Comedications/other treatments while in the study: any Control Description: standard practice. The attending physician presented the PNES diagnosis at his/her own discretion (without a script) and suggested mental health follow‐up in the community. These patients did not receive an inpatient psychiatric consultation or educational materials, and the study team did not contact them until eight weeks after discharge Length of treatment: 5 weeks Longest follow‐up after end of treatment: 3 weeks Comedications/other treatments while in the study: any
Outcomes	Mental state – depression (BDI) Outcome type: continuous Quality of life (QOLIE10‐P) Outcome type: continuous Seizure frequency (self‐made scale) Outcome type: continuous
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "a preset randomisation chart that was based on computer generation of random numbers (simple randomisation)."
Allocation concealment (selection bias)	Unclear risk	No information provided.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	No information provided.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No information provided.
Incomplete outcome data (attrition bias) All outcomes	High risk	The distribution of dropouts among groups was not specified.
Selective reporting (reporting bias)	Unclear risk	No protocol available.
Other bias	High risk	Primary outcome was measured on a self‐made scale.