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. 2020 Jul 17;2020(7):CD005331. doi: 10.1002/14651858.CD005331.pub3

Moene 2003.

Study characteristics
Methods Study design: randomised controlled trial
Study grouping: parallel group
Adequate power (evidence of power calculation): No. Quote: "Another limitation is the lack of power of the study because of the small sample size".
Allocation concealment method: participants were told they would receive same treatment, only at different starting points.
Blinding of outcome assessors: 3 trained and independent raters blind to group membership and study rational rated the performance of motor tasks.
Check of blinding: no information provided
Duration of study: 1991–1996
Randomisation method: block randomisation
Participants Baseline characteristics
Intervention
  • n: 24


Control
  • n: 25


Overall
  • n: 49

  • Duration of symptoms: 3.7 years

  • Age (mean): 36.6 (SD 11.0) years

  • Sex (% woman): 75%

  • Marital status currently married (%): 75%

  • Educational status: 20.5% had higher education


Inclusion criteria: positive diagnosis of conversion disorder, motor type (such as paresis or paralysis, gait disturbances, co‐ordinations problems, aphonia, seizures, or pseudo‐epileptic seizures with motor activity) or a diagnosis of somatisation disorder with conversion symptoms, motor type according to DSM‐III‐R criteria; duration of symptoms ≥ 1 month; aged 18–65 years; no problem speaking the Dutch language; available for full course of treatment and assessment sessions; no other psychological treatment during the project; no imminent change in medication.
Exclusion criteria: evidence of a neurological disorder explaining the conversion symptom;  major affective disorder or other severe psychiatric diagnosis requiring immediate treatment.
Pretreatment: no significant differences between groups with respect to demographic variable, psychiatric history or dependent values at baseline. All Chi2 P values were > 0.15.
Interventions Intervention characteristics
Intervention
  • Description: 10 weekly 1‐hour sessions, preceded by introductory session. Self‐hypnosis as homework between sessions.

  • Length of treatment: 3 months

  • Longest follow‐up after end of treatment: 6 months

  • Comedications/other treatments while in the study: some participants received further hypnosis sessions if needed after end of treatment at 3 months.


Control
  • Description: wait list

  • Length of treatment: 3 months

  • Longest follow‐up after end of treatment: none

  • Comedications/other treatments while in the study: none

Outcomes Severity of impairment (VRMC)
  • Outcome type: continuous


Dropout
  • Outcome type: dichotomous

  • Data value: endpoint

Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method used for randomisation was not provided.
Allocation concealment (selection bias) Unclear risk All participants knew they would get the same treatment at different times. No evidence of this being a problem.
Blinding of participants and personnel (performance bias)
All outcomes High risk All participants knew they would get the same treatment as informed of cross‐over study.
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk 2 trained and independent raters viewed the pretreatment video followed randomly by the posttreatment or follow‐up video.
Incomplete outcome data (attrition bias)
All outcomes High risk Incomplete data as data were not reported for the 2 groups (control and intervention) separately. Dropouts accounted for. But no baseline characteristics reported.
Selective reporting (reporting bias) Unclear risk Results only reported for end of treatment, as follow‐up data were not comparable, as the control/wait list group had started treatment.
Other bias Low risk None described.