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. 2020 Jul 17;2020(7):CD005331. doi: 10.1002/14651858.CD005331.pub3

Mousavi 2008.

Study characteristics
Methods Study design: randomised controlled trial
Study grouping: parallel group
Adequate power (evidence of power calculation): no information provided
Allocation concealment method: no information provided
Blinding of outcome assessors: not blinded to assist treatment alliance
Check of blinding: no information provided
Duration of study: 2005–2006
Randomisation method: no information provided
Participants Baseline characteristics
Intervention
  • n: 20


Control
  • n: 20


Overall
  • n: 40

  • Sex (% woman): 66%

  • Educational status: regarding patients’ educational level: 5 were illiterate (6%), 17 had finished primary school (21%), 9 secondary school (24%) and 29 high school (36%). 10 (13%) participants had university qualification.


Inclusion criteria: outpatient referrals with conversion disorder except epileptiform subtype; aged 10–50 years; onset of illness in the past 24 hours; no history of conversion disorder in the year before study
Exclusion criteria: non‐consenting patients or careers; non‐compliance after initial agreement; failing to enter in trance state; no accessibility for 1‐month follow‐up after treatment.
Pretreatment: uncertain. No baseline demographics given per groups.
Interventions Intervention characteristics
Intervention
  • Description: hypnosis. The psychiatrist used hypnosis to put the participants in a trance state

  • Length of treatment: 2 hours

  • Longest follow‐up after end of treatment: 1 month

  • Co‐medications/other treatments while in the study: participants and their families were educated about the symptoms and relapse signature and the role of psychosocial stressors as precipitating factors. Medication was used to treat any comorbid mood or anxiety disorders.


Control
  • Description: diazepam (intravenous injection, 5 mg in 1 minute)

  • Length of treatment: 2 hours

  • Longest follow‐up after end of treatment: 1 month

  • Comedications/other treatments while in the study: participants and their families were educated about the symptoms and relapse signature and the role of psychosocial stressors as precipitating factors. Medication was used to treat any comorbid mood or anxiety disorders.


The study included two other interventions, relaxation and suggestion, which were not relevant to the review.
Outcomes Symptom freedom
  • Outcome type: dichotomous


Relapse
  • Outcome type: dichotomous

Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Quote: "We managed to include 20 patients in each group randomly."
Comment: no information on how this was done.
Allocation concealment (selection bias) Unclear risk No information provided.
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk No information provided.
Blinding of outcome assessment (detection bias)
All outcomes High risk Quote: "the psychiatrist who carried out the assessment and the therapeutic works was not blind to the intervention groups. This was to improve the rapport and therapeutic relationship, which is necessary for treatment of conversion disorder."
Incomplete outcome data (attrition bias)
All outcomes High risk Unclear what the outcomes were and how the outcomes were measured. There was a lack of untreated controls.
Selective reporting (reporting bias) High risk No baseline characteristics, or individual group data
Other bias Low risk No apparent sources of bias.