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. 2019 Dec 20;3:100032. doi: 10.1016/j.jtauto.2019.100032

Fig. 1.

Fig. 1

Untreated patients have lower alpha diversity than controls. Rarefied relative abundance of fecal bacteria of controls (n ​= ​39) and untreated MS patients (n ​= ​26) was used to calculate alpha and beta diversity. a) Rarefaction curves were calculated at multiple sequence depths for Shannon index for controls and untreated patients with MS. Graphs depict average ​± ​standard error (left panel). Statistical significance was calculated at the maximum depth (10,385) using a Wilcoxon rank sum test (right panel). b) Beta diversity was calculated using unweighted UniFrac (left panel) and weighted UniFrac (right panel). ANOSIM was used to determine differences in MS and healthy controls. * p ​< ​0.05, ** p ​< ​0.01.