Table 1.
Prescription pattern of pilocarpine, humectants/lubricants for topical use and disease-modifying antirheumatic drugs for patients diagnosed with Sjögren's syndrome, Colombia.
| Drug | Frequency (n = 4945) | % |
|---|---|---|
| Symptomatic treatment | 4134 | 83.6 |
| -Oral pilocarpine | 365 | 7.4 |
| Monotherapy | 166 | 3.4 |
| Associated with topical therapy | 199 | 4.0 |
| -Lubricants and ocular humectants | 3906 | 79.0 |
| Hyaluronate | 1326 | 26.8 |
| Polyacrylic acid | 1002 | 20.3 |
| Carboxymethylcellulose + glycerin | 819 | 16.6 |
| Carboxymethylcellulose | 766 | 15.5 |
| Hyaluronate + chondroitin | 607 | 12.3 |
| Ciclosporin | 133 | 2.7 |
| Hydroxypropylmethylcellulose | 106 | 2.1 |
| Carboxymethylcellulose + glycerin + polysorbate | 14 | 0.3 |
| -Artificial saliva | 15 | 0.3 |
| Treatment with disease-modifying antirheumatics | 605 | 12.2 |
| -Conventional | 587 | 11.9 |
| Methotrexate | 229 | 4.6 |
| Chloroquine | 200 | 4.0 |
| Azathioprine | 103 | 2.1 |
| Sulfasalazine | 80 | 1.6 |
| Leflunomide | 75 | 1.5 |
| Hydroxychloroquine | 61 | 1.2 |
| -Biological | 62 | 1.3 |
| Rituximab | 15 | 0.3 |
| Etanercept | 10 | 0.2 |
| Golimumab | 8 | 0.2 |
| Others (8 different biotechnologies) | 29 | 0.6 |
| Immunosuppressants | 509 | 10.3 |
| -Systemic corticosteroids | 506 | 10.2 |
| Prednisolone | 281 | 5.7 |
| Dexamethasone | 141 | 2.9 |
| Deflazacort | 40 | 0.8 |
| Prednisone | 33 | 0.7 |
| Other (3 different corticosteroids) | 46 | 0.9 |
| -Other immunosuppressants (3 different) | 22 | 0.4 |