Table 2.

Discordant familial risks of Graves disease.

Subtypes of AID in offspring	Family history of AID	Obs.	SIR	95% CI
Graves	Addison disease	53	2.24	1.68	2.88
Addison disease	Graves	47	1.76	1.29	2.29
Graves	Amyotrophic lateral sclerosis	127	1.33	1.11	1.57
Graves	Celiac disease	268	1.73	1.53	1.95
Celiac disease	Graves	759	1.86	1.73	2.00
Crohn disease	Graves	472	1.10	1.00	1.20
Graves	Dermatitis herpetiformis	39	1.85	1.32	2.48
Dermatitis herpetiformis	Graves	46	2.38	1.74	3.12
Graves	Diabetes mellitus type I	141	1.78	1.50	2.08
Diabetes mellitus type I	Graves	630	1.85	1.71	2.00
Graves	Discoid lupus erythematosus	50	1.52	1.13	1.97
Graves	Hashimoto thyroiditis	584	2.04	1.88	2.21
Hashimoto thyroiditis	Graves	760	1.97	1.84	2.12
Graves	Lupoid hepatitis	74	1.30	1.02	1.61
Lupoid hepatitis	Graves	68	1.27	0.98	1.59
Graves	Myasthenia gravis	57	1.52	1.15	1.95
Myasthenia gravis	Graves	47	1.57	1.15	2.05
Graves	Pernicious anemia	127	1.94	1.61	2.29
Graves	Polymyalgia rheumatica	395	1.12	1.01	1.23
Graves	Polymyositis/dermatomyositis	42	1.58	1.14	2.10
Polymyositis/dermatomyositis	Graves	32	1.47	1.00	2.02
Graves	Primary biliary cirrhosis	56	1.36	1.03	1.74
Graves	Psoriasis	1278	1.18	1.12	1.25
Psoriasis	Graves	1672	1.20	1.14	1.26
Reiter disease	Graves	29	1.58	1.06	2.21
Graves	Rheumatic fever	52	1.31	0.98	1.69
Graves	Rheumatoid arthritis	1517	1.37	1.30	1.44
Rheumatoid arthritis	Graves	883	1.28	1.19	1.36
Graves	Sarcoidosis	257	1.32	1.16	1.49
Sarcoidosis	Graves	278	1.25	1.11	1.40
Graves	Sjögrensyndrome	141	1.43	1.20	1.68
Sjögrensyndrome	Graves	109	1.24	1.02	1.48
Graves	Systemic lupus erythematosus	141	1.71	1.44	2.00
Systemic lupus erythematosus	Graves	120	1.50	1.24	1.78
Graves	Systemic sclerosis	57	1.66	1.26	2.12
Systemic sclerosis	Graves	36	1.38	0.97	1.87
Graves	Ulcerative colitis	577	1.15	1.06	1.25
Ulcerative colitis	Graves	859	1.19	1.11	1.27
Graves	Wegener granulomatosis	40	1.40	1.00	1.86