Table 3.
Discordant familial risks of Hashimoto thyroiditis.
Subtypes of AID in offspring | Family history of AID | Obs. | SIR | 95% CI | |
---|---|---|---|---|---|
Hashimoto thyroiditis | Addison disease | 47 | 2.39 | 1.75 | 3.12 |
Addison disease | Hashimoto thyroiditis | 35 | 2.04 | 1.42 | 2.77 |
Hashimoto thyroiditis | Autoimmune hemolytic anemia | 16 | 2.11 | 1.20 | 3.27 |
Hashimoto thyroiditis | Celiac disease | 242 | 1.39 | 1.22 | 1.57 |
Celiac disease | Hashimoto thyroiditis | 504 | 1.59 | 1.46 | 1.74 |
Hashimoto thyroiditis | Chronic rheumatic heart disease | 163 | 1.23 | 1.05 | 1.43 |
Hashimoto thyroiditis | Crohn disease | 325 | 1.25 | 1.12 | 1.39 |
Crohn disease | Hashimoto thyroiditis | 348 | 1.24 | 1.11 | 1.37 |
Hashimoto thyroiditis | Dermatitis herpetiformis | 25 | 1.56 | 1.01 | 2.22 |
Hashimoto thyroiditis | Diabetes mellitus type I | 191 | 1.71 | 1.47 | 1.96 |
Diabetes mellitus type I | Hashimoto thyroiditis | 431 | 1.65 | 1.49 | 1.80 |
Hashimoto thyroiditis | Glomerular nephritis chronic | 126 | 1.19 | 0.99 | 1.41 |
Glomerular nephritis chronic | Hashimoto thyroiditis | 105 | 1.22 | 1.00 | 1.46 |
Hashimoto thyroiditis | Graves | 760 | 1.97 | 1.84 | 2.12 |
Hashimoto thyroiditis | Immune thrombocytopenic purpura | 87 | 1.29 | 1.03 | 1.58 |
Immune thrombocytopenic purpura | Hashimoto thyroiditis | 95 | 1.25 | 1.01 | 1.51 |
Pemphigus | Hashimoto thyroiditis | 14 | 2.05 | 1.12 | 3.26 |
Hashimoto thyroiditis | Pernicious anemia | 74 | 1.74 | 1.37 | 2.16 |
Hashimoto thyroiditis | Polymyalgia rheumatica | 292 | 1.23 | 1.10 | 1.38 |
Primary biliary cirrhosis | Hashimoto thyroiditis | 25 | 1.63 | 1.05 | 2.33 |
Hashimoto thyroiditis | Psoriasis | 1075 | 1.15 | 1.08 | 1.22 |
Psoriasis | Hashimoto thyroiditis | 1078 | 1.22 | 1.15 | 1.29 |
Hashimoto thyroiditis | Reiter disease | 4 | 0.31 | 0.08 | 0.70 |
Hashimoto thyroiditis | Rheumatoid arthritis | 1148 | 1.41 | 1.33 | 1.50 |
Rheumatoid arthritis | Hashimoto thyroiditis | 631 | 1.51 | 1.39 | 1.63 |
Hashimoto thyroiditis | Sarcoidosis | 191 | 1.19 | 1.03 | 1.36 |
Hashimoto thyroiditis | Sjögren syndrome | 114 | 1.43 | 1.18 | 1.70 |
Hashimoto thyroiditis | Systemic lupus erythematosus | 89 | 1.36 | 1.09 | 1.66 |
Systemic lupus erythematosus | Hashimoto thyroiditis | 74 | 1.49 | 1.17 | 1.84 |
Hashimoto thyroiditis | Takayasu disease | 6 | 2.57 | 0.93 | 5.05 |
Takayasu disease | Hashimoto thyroiditis | 5 | 2.57 | 0.81 | 5.32 |