Table 4.
Correlations of gene expression of BAFF and APRIL cytokines, and their receptors (BR3 and TACI), with lupus activity parameters and renal parameters in the urinary sediment of patients with LN.
| uBAFF |
uAPRIL |
uBR3 |
uTACI |
|||||
|---|---|---|---|---|---|---|---|---|
| Spearman’s rank | p-value | Spearman’s rank | p-value | Spearman’s rank | p-value | Spearman’s rank | p-value | |
| Lupus activity parameters | ||||||||
| Anti-dsDNA (IFI) | 0.02 | 0.936 | −0.16 | 0.396 | 0.32 | 0.086 | 0.20 | 0.295 |
| Anti-dsDNA (ELISA) | −0.03 | 0.860 | −0.10 | 0.598 | 0.48 | 0.005 | 0.40 | 0.024 |
| Low C3 | 0.13 | 0.536 | 0.32 | 0.115 | −0.12 | 0.563 | 0.02 | 0.990 |
| Low C4 | 0.27 | 0.233 | 0.11 | 0.635 | 0.21 | 0.357 | 0.49 | 0.023 |
| SLEDAI-2K index | −0.07 | 0.710 | −0.20 | 0.242 | 0.33 | 0.049 | 0.10 | 0.579 |
| Renal parameters | ||||||||
| Serum creatinine | 0.29 | 0.089 | 0.10 | 0.569 | 0.20 | 0.242 | 0.12 | 0.478 |
| Blood urea nitrogen | 0.15 | 0.380 | 0.22 | 0.197 | 0.21 | 0.226 | 0.14 | 0.422 |
| Proteinuria/creatinuria ratio | 0.05 | 0.798 | −0.02 | 0.906 | −0.20 | 0.253 | −0.12 | 0.493 |
| Epithelial cell casts | −0.12 | 0.487 | 0.51 | 0.002 | 0.11 | 0.536 | −0.10 | 0.556 |
| Granular casts | 0.06 | 0.713 | 0.07 | 0.675 | 0.50 | 0.002 | 0.45 | 0.007 |
| Hyaline casts | −0.14 | 0.419 | −0.20 | 0.243 | 0.28 | 0.098 | 0.04 | 0.806 |
| Haematuria | 0.23 | 0.188 | 0.28 | 0.099 | 0.31 | 0.066 | 0.16 | 0.357 |
| Activity index | −0.02 | 0.888 | 0.13 | 0.461 | 0.35 | 0.039 | 0.24 | 0.165 |
| Chronicity index | 0.11 | 0.548 | −0.23 | 0.192 | −0.19 | 0.276 | −0.17 | 0.322 |
uBAFF, urinary B-cell activating factor of the tumor necrosis factor family; uAPRIL, urinary a proliferation-inducing ligand; uBR3, urinary BLyS receptor 3; uTACI, urinary transmembrane activator and cyclophilin ligand interactor; uBCMA, urinary B-cell maturation antigen; Anti-dsDNA, Anti-double stranded DNA; IFI, Indirect Immunofluorescence; ELISA, Enzyme-Linked ImmunoSorbent Assay, SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index 2000).
point out the significant values obtained from the correlation analysis, it means, all the p-values <0.05.
Are all the values obtained from the correlation analysis, both the significant and the non-significant.
Are the headings of each column with the names of the parameters and the cytokines/cytokines receptors that where measured, with the statistical test carried out to obtain a p-value in each one.