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. 2020 Jul 13;44(3):1037–1048. doi: 10.3892/or.2020.7686

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Copyright: © Jeddo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — MELK knockdown reduces migration and invasion in vitro. (A) Wound healing assays revealed the reduced migratory potential of cells following knockdown of MELK. (B) Transwell assays revealed reduced migratory and invasive potential of MNNG/HOS cells following knockdown of MELK. (C) Migration (wound healing assay) and (D) migration and invasion (Transwell assays) were reduced in osteosarcoma cells following treatment with OTSSP167. **P<0.01, ***P<0.001. MELK, maternal embryonic leucine zipper kinase.