Table 2.
Clinical characteristics of the study population
| Advanced BA group | Control group | p-value | |
|---|---|---|---|
| Basic LH (IU/L) | 0.24 (0.15, 0.42) | 0.24 (0.13, 0.44) | 0.902 |
| Peak LH (IU/L) | 3.49 (2.52, 4.18) | 3.57 (2.80, 4.16) | 0.301 |
| Peak LH/peak FSH | 0.22 (0.17, 0.29) | 0.21 (0.16, 0.29) | 0.316 |
| DHEAS (µg/dL) | 42.85 (23.78, 60.83) | 29.50 (16.80, 52.40) | < 0.001 |
| DHEAS SDS | 1.94 (0.46, 4.15) | 0.85 (-0.14, 2.47) | < 0.001 |
| Androsterone (ng/mL) | 0.30 (0.15, 0.48) | 0.15 (0.15, 0.35) | < 0.001 |
| Insulin (µIU/mL) | 6.68 (5.08, 9.37) | 5.50 (3.56, 8.10) | < 0.001 |
| SHBG (nmol/L) | 58.15 (41.75, 75.23) | 71.70 (52.80, 89.90) | < 0.001 |
| IGF-1 (ng/mL) | 238.00 (190.00, 300.25) | 204.00 (168.00, 241.00) | < 0.001 |
| IGF-1 SDS | 0.44 (-0.30, 1.29) | -0.27 (-0.73, 0.48) | < 0.001 |
| Oestradiol (pmol/L) | 10.00 (10.00, 20.00) | 10.00 (10.00, 10.00) | 0.257 |
| Triglyceride (mmol/L) | 0.80 (0.61, 1.04) | 0.85 (0.63, 1.05) | 0.366 |
| Total cholesterol (mmol/L) | 3.76 (3.37, 4.35) | 3.86 (3.49, 4.34) | 0.299 |
| HDL (mmol/L) | 1.23 (1.06, 1.38) | 1.23 (1.05, 1.42) | 0.646 |
| LDL (mmol/L) | 2.27 (1.96, 2.63) | 2.36 (2.07, 2.69) | 0.215 |
| Uterine length (cm) | 3.41(3.08,3.67) | 3.27(2.93,3.49) | 0.009 |
| Ovarian volume (ml) | 1.23(0.82,1.74) | 1.13(0.78,1.76) | 0.389 |
Data presented as the median and quartiles
BA Bone age, LH Luteinizing hormone, FSH Follicle-stimulating hormone, DHEAS Dehydroepiandrosterone sulfate, SDS Standard deviation score, SHBG Sex hormone binding globulin, IGF-1 Insulin-like growth factor-1, HDL High-density lipoprotein, LDL Low-density lipoprotein