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. 2020 Jul 29;18:118. doi: 10.1186/s12964-020-00614-w

Table 4.

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vWAT ND REACTOME PATHS (27)
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Autodegradation of Cdh1 by Cdh1:APC/C
CDK-mediated phosphorylation and removal of Cdc6
CDT1 association with the CDC6:ORC:origin complex
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Cross-presentation of soluble exogenous antigens (endosomes)
Defective CFTR causes cystic fibrosis
Degradation of AXIN
Eukaryotic Translation Termination
Formation of a pool of free 40S subunits
Hh mutants abrogate ligand secretion
Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD
HSF1 activation
L13a-mediated translational silencing of Ceruloplasmin expression
Mycobacterium tubercolisis biological processes
Orc1 removal from chromatin
Peptide chain elongation
Platelet degranulation
Post-translational protein phosphorylation
Regulation of activated PAK-2p34 by proteasome mediated degradation
Regulation of ornithine decarboxylase (ODC)
Regulation of RAS by GAPs
Response to elevated platelet cytosolic Ca2+
SCF-beta-TrCP mediated degradation of Emi1
Selenocysteine synthesis
Vif-mediated degradation of APOBEC3G
sWAT ND REACTOME PATHS (13)
Anchoring fibril formation
Assembly of collagen fibrils and other multimeric structures
Cross-presentation of soluble exogenous antigens (endosomes)
Crosslinking of collagen fibrils
Elastic fibre formation
Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD
Laminin interactions
Mycobacterium tuberculosis biological processes
Post-translational protein phosphorylation
Prefoldin mediated transfer of substrate to CCT/TriC
Regulation of ornithine decarboxylase (ODC)
SCF-beta-TrCP mediated degradation of Emi1
Vif-mediated degradation of APOBEC3G
BM ND REACT PATHS (17)
Assembly of collagen fibrils and other multimeric structures
Collagen chain trimerization
Collagen degradation
Cross-presentation of soluble exogenous antigens (endosomes)
Crosslinking of collagen fibrils
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective CHST6 causes MCDC1
Defective ST3GAL3 causes MCT12 and EIEE15
Diseases associated with glycosaminoglycan metabolism
ECM proteoglycans
Elastic fibre formation
Laminin interactions
Molecules associated with elastic fibres
Platelet degranulation
Post-translational protein phosphorylation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
SCF-beta-TrCP mediated degradation of Emi1