Table 5.
.
| vWAT HFD REACTOME PATHS (25) | |
| Anchoring fibril formation | |
| APC/C:Cdc20 mediated degradation of Securin | |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | |
| Assembly of collagen fibrils and other multimeric structures | |
| Autodegradation of Cdh1 by Cdh1:APC/C | |
| CDK-mediated phosphorylation and removal of Cdc6 | |
| CDT1 association with the CDC6:ORC:origin complex | |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |
| Collagen chain trimerization | |
| Collagen degradation | |
| Cross-presentation of soluble exogenous antigens (endosomes) | |
| Crosslinking of collagen fibrils | |
| Defective CFTR causes cystic fibrosis | |
| Degradation of AXIN | |
| Hh mutants abrogate ligand secretion | |
| Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD | |
| HSF1 activation | |
| Orc1 removal from chromatin | |
| Platelet degranulation | |
| Post-translational protein phosphorylation | |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | |
| Regulation of ornithine decarboxylase (ODC) | |
| Regulation of RAS by GAPs | |
| SCF-beta-TrCP mediated degradation of Emi1 | |
| Vif-mediated degradation of APOBEC3G | |
| sWAT HFD REACT PATHS (15) | |
| Assembly of collagen fibrils and other multimeric structures | |
| Autodegradation of Cdh1 by Cdh1:APC/C | |
| Cross-presentation of soluble exogenous antigens (endosomes) | |
| Crosslinking of collagen fibrils | |
| Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | |
| Elastic fibre formation | |
| Hh mutants abrogate ligand secretion | |
| Hh mutants that don’t undergo autocatalytic processing are degraded by ERAD | |
| Laminin interactions | |
| Mycobacterium tuberculosis biological processes | |
| Platelet degranulation | |
| Post-translational protein phosphorylation | |
| Regulation of ornithine decarboxylase (ODC) | |
| SCF-beta-TrCP mediated degradation of Emi1 | |
| Vif-mediated degradation of APOBEC3G | |
| BM HFD REACT PATHS (20) | |
| Anchoring fibril formation | |
| Assembly of collagen fibrils and other multimeric structures | |
| Collagen biosynthesis and modifying enzymes | |
| Collagen chain trimerization | |
| Collagen degradation | |
| Collagen formation | |
| Cross-presentation of soluble exogenous antigens (endosomes) | |
| Crosslinking of collagen fibrils | |
| Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | |
| Degradation of the extracellular matrix | |
| ECM proteoglycans | |
| Elastic fibre formation | |
| HSF1 activation | |
| Laminin interactions | |
| Molecules associated with elastic fibres | |
| NCAM1 interactions | |
| Neutrophil degranulation | |
| Platelet degranulation | |
| Post-translational protein phosphorylation | |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |