Table 2.

Necrosis rate and apoptotic rate of the RAW264.7 cells under the different treatments

Groups	N	Apoptosis rate	Necrosis rate
Control	6	3.30 ± 1.01	2.21 ± 0.21
LEV	6	6.60 ± 1.78*	2.28 ± 0.35
LEV-NPs	6	10.42 ± 0.84*#	4.20 ± 1.04*#
US	6	8.76 ± 0.78*	9.54 ± 0.88*#
LEV + US	6	15.54 ± 1.30*#	7.82 ± 044*#
LEV-NPs + US	6	21.25 ± 1.15*#	8.21 ± 0.66*#

LEV: levofloxacin; LEV-NPs: levofloxacin-loaded PLGA nanoparticles; US: ultrasonic; SD: standard deviation

Compared with the control, ^*P < 0.05; compared with the LEV, ^#P < 0.05. Data represent the mean ± SD