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. 2020 May 19;20(2):952–960. doi: 10.3892/etm.2020.8770

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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miR-187-3p overexpression reduced cell viability and increased cell apoptosis in MDA-MB-231 cells. (A) Transfection with miR-187-3p mimic significantly increased miR-187-3p expression compared with those transfected with miR-NC mimic in MDA-MB-231 cells. ^***P<0.001 as indicated. (B) Compared with miR-NC mimic, transfection with miR-187-3p mimic significantly reduced MDA-MB-231 cell viability and (C) increased cell apoptosis in MDA-MB-231 cells. ^**P<0.01 as indicated. (D) Quantified data from (C) demonstrating that transfection with miR-187-3p mimic significantly increased MDA-MB-231 cell apoptosis. Data are presented as the mean ± standard deviation. ^*P<0.05 as indicated. miR, microRNA; NC, negative control.