Skip to main content
. 2020 May 19;20(2):952–960. doi: 10.3892/etm.2020.8770

Figure 3.

Figure 3

miR-187-3p enhanced the gemcitabine-mediated reduction in cell viability and induction of MDA-MB-231 cell apoptosis. (A) Gemcitabine treatment (2 nM) did not alter miR-187-3p expression in MDA-MB-231 cells. (B) Transfection with miR-187-3p mimic significantly enhanced gemcitabine-mediated reduction in MDA-MB-231 cell viability compared with those transfected with miR-NC mimic. ***P<0.001 as indicated. (C) Treatment with 2 nM gemcitabine significantly increased MDA-MB-231 cell apoptosis compared with the control, which was in turn, significantly potentiated following transfection with the miR-187-3p mimic. **P<0.01 as indicated. (D) Representative flow cytometry dot plots complementing the quantified data from (C) Data are presented as the mean ± standard deviation. miR, microRNA; NC, negative control.