Summary of findings 1. Cognitive behavioral interventions to improve adherence.
Nutrional intervention plus behavioural management training (BEH) compared with Nutritional intervention alone (NUT)for children with CF (4‐12 years) | ||||
Patient or population: Children from 4‐12 years with a diagnosis of CF by sweat test, pancreatic insufficiency; and weight for age and height < 40th percentile Settings: group setting Intervention: Nutrional intervention plus behavioural management training Comparison: Nutritional intervention alone | ||||
Outcomes | Illustrative comparative risks* (95% CI) | No of Participants (studies) | Comments | |
Assumed risk | Corresponding risk | |||
Nutritional intervention alone | Nutrional intervention plus behavioural management training | |||
Change in weight pre‐ and post‐treatment in (kg) |
The mean change in weight ranged across control groups from 0.92 to 1.75kg | The mean change in weight in the intervention groups was
0.11kghigher (0.84 lower to 1.07 higher) |
75 (2) | Primary outcome |
BMIz change range: ‐1.00 to 1.00 2‐year follow up |
The mean BMIz change in the control group was ‐0.22 | The mean BMIz change in the intervention group was
0.35 higher (0 to 0.7 higher) |
67 (1) | Primary outcome |
Total calories per day post‐intervention |
The mean total calories per day ranged across control groups from 1316 to 2315 calories | The mean total calories per day in the intervention groups was 275.8 calories higher (66.65 to 485.05 higher) | 83 (3) | Secondary outcome |
Change in calorie intake pre‐ and post‐treatment |
The mean change in calorie intake ranged across control groups from 303.9 to 489 calories | The mean change in calorie intake in the intervention groups was 364.06 calories higher (191.99 to 536.13 higher) | 82 (3) | Secondary outcome |
Estimated energy requirements (%EER) post‐intervention |
The mean %EER in the control group was 127% | The mean %EER in the intervention group was 21% higher (7.76 to 34.24 higher) | 67 (1) | Secondary outcome |
Change in estimated energy requirements (%EER) pre‐ and post‐treatment |
The mean of change in %EER in the control group was 27% | The mean of change in %EER in the intervention groups was
21% higher (9.22 to 32.78 higher) |
67 (1) | Secondary outcome |
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval |