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. 2020 Jul 13;2020:2189189. doi: 10.1155/2020/2189189

Table 8.

Effect of area under the oral glucose tolerance curve values of the polyherbal drug in streptozotocin-induced diabetic rats.

Group Area under the oral glucose tolerance curve values (mmol/L·h)
½ h 1 h 2 h 3 h 4 h Total
Healthy control rats 3.44 ± 0.09 3.93 ± 0.17 6.21 ± 0.24 5.23 ± 0.09 4.74 ± 0.04 23.55 ± 0.63
Diabetic control rats 7.42 ± 0.17 8.26 ± 0.23 15.40 ± 0.41 14.17 ± 0.34 13.05 ± 0.39 58.30 ± 1.54
Diabetic rats + cold water extract (0.5 g/kg) 6.86 ± 0.24 7.67 ± 0.08 14.02 ± 0.13 12.06 ± 0.26 11.13 ± 0.46 51.74 ± 1.17
Diabetic rats + cold water extract (1.0 g/kg) 7.17 ± 0.11 7.86 ± 0.12 13.51 ± 0.21 11.45 ± 0.35 9.60 ± 0.25 49.59 ± 1.04
Diabetic rats + cold water extract (1.5 g/kg) 6.78 ± 0.25 7.00 ± 0.27 12.40 ± 0.46 10.38 ± 0.27 4.25 ± 0.36 40.81 ± 1.61
Diabetic rats + hot water extract (0.5 g/kg) 6.93 ± 0.20 7.50 ± 0.25 13.63 ± 0.39 11.92 ± 0.18 10.60 ± 0.19 50.58 ± 1.21
Diabetic rats + hot water extract (1.0 g/kg) 6.75 ± 0.07 7.11 ± 0.06 11.92 ± 0.19 10.73 ± 0.37 9.96 ± 0.49 46.47 ± 1.18
Diabetic rats + hot water extract (1.5 g/kg) 7.04 ± 0.21 7.09 ± 0.16 11.43 ± 0.30 9.63 ± 0.41 8.34 ± 0.19 43.53 ± 1.27
Diabetic rats + acetone : water extract (0.5 g/kg) 7.23 ± 0.05 7.52 ± 0.14 12.08 ± 0.90 10.86 ± 0.82 10.70 ± 0.32 48.39 ± 2.23
Diabetic rats + acetone : water extract (1.0 g/kg) 7.30 ± 0.18 6.88 ± 0.08 10.72 ± 0.28 9.91 ± 0.30 9.12 ± 0.36 43.94 ± 1.20
Diabetic rats + acetone : water extract (1.5 g/kg) 7.36 ± 0.10 7.02 ± 0.15 10.36 ± 0.21 9.01 ± 0.17 8.24 ± 0.20 41.99 ± 0.83
Diabetic rats + glibenclamide (0.5 mg/kg) 7.19 ± 0.19 6.55 ± 0.20 9.22 ± 0.46 7.48 ± 0.30 6.00 ± 0.36 36.44 ± 1.51

The values are expressed as mean ± SEM (n = 6/group). Data were analyzed by ANOVA followed by Dunnett's test (p < 0.05). Results are significant compared to the control group at p < 0.05.