Table 8.
Group | Area under the oral glucose tolerance curve values (mmol/L·h) | |||||
---|---|---|---|---|---|---|
½ h | 1 h | 2 h | 3 h | 4 h | Total | |
Healthy control rats | 3.44 ± 0.09 | 3.93 ± 0.17 | 6.21 ± 0.24 | 5.23 ± 0.09 | 4.74 ± 0.04 | 23.55 ± 0.63 |
Diabetic control rats | 7.42 ± 0.17 | 8.26 ± 0.23 | 15.40 ± 0.41 | 14.17 ± 0.34 | 13.05 ± 0.39 | 58.30 ± 1.54 |
Diabetic rats + cold water extract (0.5 g/kg) | 6.86 ± 0.24∗ | 7.67 ± 0.08∗ | 14.02 ± 0.13∗ | 12.06 ± 0.26∗ | 11.13 ± 0.46∗ | 51.74 ± 1.17∗ |
Diabetic rats + cold water extract (1.0 g/kg) | 7.17 ± 0.11∗ | 7.86 ± 0.12∗ | 13.51 ± 0.21∗ | 11.45 ± 0.35∗ | 9.60 ± 0.25∗ | 49.59 ± 1.04∗ |
Diabetic rats + cold water extract (1.5 g/kg) | 6.78 ± 0.25∗ | 7.00 ± 0.27∗ | 12.40 ± 0.46∗ | 10.38 ± 0.27∗ | 4.25 ± 0.36∗ | 40.81 ± 1.61∗ |
Diabetic rats + hot water extract (0.5 g/kg) | 6.93 ± 0.20 | 7.50 ± 0.25 | 13.63 ± 0.39 | 11.92 ± 0.18 | 10.60 ± 0.19 | 50.58 ± 1.21 |
Diabetic rats + hot water extract (1.0 g/kg) | 6.75 ± 0.07 | 7.11 ± 0.06 | 11.92 ± 0.19∗ | 10.73 ± 0.37∗ | 9.96 ± 0.49∗ | 46.47 ± 1.18∗ |
Diabetic rats + hot water extract (1.5 g/kg) | 7.04 ± 0.21 | 7.09 ± 0.16 | 11.43 ± 0.30∗ | 9.63 ± 0.41∗ | 8.34 ± 0.19∗ | 43.53 ± 1.27∗ |
Diabetic rats + acetone : water extract (0.5 g/kg) | 7.23 ± 0.05 | 7.52 ± 0.14 | 12.08 ± 0.90∗ | 10.86 ± 0.82∗ | 10.70 ± 0.32∗ | 48.39 ± 2.23∗ |
Diabetic rats + acetone : water extract (1.0 g/kg) | 7.30 ± 0.18 | 6.88 ± 0.08∗ | 10.72 ± 0.28∗ | 9.91 ± 0.30∗ | 9.12 ± 0.36∗ | 43.94 ± 1.20∗ |
Diabetic rats + acetone : water extract (1.5 g/kg) | 7.36 ± 0.10 | 7.02 ± 0.15 | 10.36 ± 0.21∗ | 9.01 ± 0.17∗ | 8.24 ± 0.20∗ | 41.99 ± 0.83∗ |
Diabetic rats + glibenclamide (0.5 mg/kg) | 7.19 ± 0.19 | 6.55 ± 0.20∗ | 9.22 ± 0.46∗ | 7.48 ± 0.30∗ | 6.00 ± 0.36∗ | 36.44 ± 1.51∗ |
The values are expressed as mean ± SEM (n = 6/group). Data were analyzed by ANOVA followed by Dunnett's test (p < 0.05). Results are significant compared to the control group at ∗p < 0.05.