Table 1 (suite 2).

Descriptive summary of 25 studies reporting the prevalence of birth defects and additional studies reporting the prevalence of sub types of birth defects among newborn in sub-Saharan African countries included in the systematic review and meta-analysis

Down syndrome	Adane and Seyoum	2018	Ethiopia	Eastern Africa	19650	10	8	0.51(0.19, 0.83)
	Ekanem et al.	2008	Nigeria	Western Africa	127929	15	8	0.12(0.06, 0.18)
	Iroha et al.	2001	Nigeria	Western Africa	22288	10	6	0.45(0.17, 0.73)
	Kishimba RS et al.	2015	Tanzania	Eastern Africa	27230	5	6	0.18(0.02, 0.34)
	Kromberg and Zwane	1993	South Africa	Southern Africa	24000	40	7	1.67(1.15, 2.19)
	Muga R et al.	2009	Kenya	Eastern Africa	7355	12	7	1.63(0.71, 2.55)
	Mukhtar-Yola M et al.	2005	Nigeria	Western Africa	13619	11	6	0.81(0.33, 1.29)
	Ochoga et al.	2018	Nigeria	Western Africa	843	10	8	11.86(4.55, 19.17)
	Taye et al.	2016	Ethiopia	Eastern Africa	319776	124	8	0.39(0.32, 0.46)
	Venter et al.	1995	South Africa	Southern Africa	7617	21	6	2.76(1.58, 3.94)
Gastrointestinal defects	Adane and Seyoum	2018	Ethiopia	Eastern Africa	19650	9	8	0.46(0.16, 0.76)
	Ekanem TB et al.	2011	Nigeria	Western Africa	39693	4	8	0.10(0.00, 0.20)
	Ekwochi et al.	2017	Nigeria	Western Africa	5830	22	7	3.77(2.20, 5.34)
	Iroha et al.	2001	Nigeria	Western Africa	22288	87	6	3.90(3.08, 4.72)
	Mekonen et al.	2015	Ethiopia	Eastern Africa	1516	5	7	3.30(0.41, 6.19)
	Mukhtar-Yola M et al.	2005	Nigeria	Western Africa	13619	29	6	2.13(1.36, 2.90)
	Ochoga et al.	2018	Nigeria	Western Africa	843	21	8	24.91(14.39, 35.43)
	Onankpa and Adamu	2014	Nigeria	Western Africa	6578	4	6	0.61(0.01, 1.21)
	Onyearugha C and Onyire B	2014	Nigeria	Western Africa	14446	22	7	1.52(0.88, 2.16)
	Taye et al.	2016	Ethiopia	Eastern Africa	319776	289	8	0.90(0.80, 1.00)
	Venter P et al.	1995	South Africa	Southern Africa	7617	9	6	1.18(0.41, 1.95)
Cardiovascular defects	Abid et al.	2014	Tunisia	North Africa	37294	255	7	6.84(6.00, 7.68)
	Adane and Seyoum	2018	Ethiopia	Eastern Africa	19650	38	8	1.93(1.32, 2.54)
	Ekwochi et al.	2017	Nigeria	Western Africa	5830	9	7	1.54(0.53, 2.55)
	Iroha et al.	2001	Nigeria	Western Africa	22288	40	6	1.79(1.24, 2.34)
	Mukhtar-Yola M et al.	2005	Nigeria	Western Africa	13619	5	6	0.37(0.05, 0.69)
	Onankpa and Adamu	2014	Nigeria	Western Africa	6578	7	6	1.06(0.27, 1.85)
	Sani et al.	2007	Nigeria	Western Africa	1499	122	7	81.39(67.55, 95.23)
	Taye et al.	2016	Ethiopia	Eastern Africa	319776	626	8	1.96(1.81, 4.84)
Unspecified defects	Adane and Seyoum	2018	Ethiopia	Eastern Africa	19650	17	8	0.87(0.46, 1.28)
	Iroha et al.	2001	Nigeria	Western Africa	22288	43	6	1.93(1.35, 2.51)
	Mukhtar-Yola M et al.	20105	Nigeria	Western Africa	13619	6	6	0.44(0.09, 0.79)
	Taye et al.	2016	Ethiopia	Eastern Africa	319776	150	8	0.47(0.39, 0.56)