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. 2020 Jul 20;2020(7):CD013684. doi: 10.1002/14651858.CD013684

Goldstein 2019.

Study characteristics
Methods Study design: RCT
Study grouping: parallel group
Unit of randomisation: individuals
Power (power & sample size calculation, level of power achieved): not specified in conference abstract/poster or abstract of manuscript under review
Imputation of missing data: no imputation of missing data; per‐protocol analysis (i.e. only participants who completed workshops) and available‐case analysis (i.e. only participants for whom outcomes were obtained)
Participants Country: USA
Setting: undergraduate students; training setting not specified
Age: mean = 20.77 (SD = 3.36) years
Sample size (randomised): 92
Sex: 36 women, 9 men (in analysed sample)
Comorbidity (mean (SD) of respective measures in indicated, if available) at baseline: not specified
Population description: undergraduate students (including health profession students)
Method of recruitment: not specified
Inclusion criteria: not specified
Exclusion criteria: not specified
Attrition (withdrawals and exclusions): pre‐intervention (assessment not completed): 3 (IG: 1, CG: 2); further withdrawals during workshops: 20 (IG: 9, CG: 11); post‐intervention (further lost to follow‐up): 9 (IG: 4, CG: 5); 3‐month follow‐up (further lost to follow‐up): 15 (IG: 7, CG: 8)
Reasons for missing data: not specified
Interventions Intervention: ‘Your Enlightened Side’ (YESplus) (n = 47)
  • delivery: face‐to‐face; probably group setting (involving some level of social interaction)

  • providers: not specified

  • duration of treatment period and timing: 4 consecutive days; 18 hours in total

  • description): primary emphasis on yogic breathing, meditation, acceptance, and social connectedness; teaches a yogic breathing and acceptance‐based approach to stress‐management

  • compliance: 37/47 completed workshop (79%); similar high ratings of the workshop in IG and CG (8.0 ± 3.1 vs 7.7 ± 3.1, respectively, on 0 ‐ 9 scale, P = 0.42)

  • integrity of delivery: not specified

  • economic information: not specified

  • theoretical basis: yogic breathing and acceptance‐based approach to stress‐management


Control: attention control: ‘Wisdom On Wellness’ (WOW) (n = 45)
  • delivery: face‐to‐face; probably group setting (involving some level of social interaction)

  • providers: not specified

  • duration of treatment period and timing): 4 consecutive days; 18 hours in total

  • description: targets cognitive stress‐management techniques; science of stress, cognitive restructuring, stress reappraisal, control strategies

  • compliance: 32/45 completed workshop (71%); similar high ratings of the workshop in IG and CG (8.0 ± 3.1 vs 7.7 ± 3.1, respectively, on 0 ‐9 scale, P = 0.42)

  • integrity of delivery: not specified

  • economic information: not specified

  • theoretical basis: cognitive approaches to stress‐management

Outcomes Outcomes collected and reported:
  • sleep ‐ PSQI

  • perceived stress ‐ PSS

  • depression ‐ MASQ, no exact findings (only significance/non‐significance) reported

  • anxiety ‐ MASQ, not reported

  • self‐esteem ‐ RSES, no exact findings (only significance/non‐significance) reported

  • social connectedness ‐ scale for Social Connectedness, no exact findings (only significance/non‐significance) reported

  • satisfaction with life ‐ Satisfaction with Life Scale, no exact findings (only significance/non‐significance) reported

  • breathing rate ‐ Maastricht Acute Stress Test (MAST)

  • heart rate ‐ MAST


Time points measured and reported: 1) pre‐intervention; 2) post‐intervention; 3) 3‐month follow‐up (3 months post‐intervention)
Adverse events: not specified
Notes Contact with authors: We contacted the authors for information on whether fostering resilience was a primary aim of the study (see miscellaneous outcomes). Since the authors gave feedback that health profession students were also included (Goldstein 2019 [pers comm]), we asked for the outcome data for this subgroup. We received no response to this inquiry.
Study start/end date: not specified in conference abstract/poster or abstract of manuscript under review
Funding source: research funded by a Mind and Life Institute Varela Award and National Science Foundation Graduate Research Fellowship
Declaration of interest: not specified in conference abstract/poster or abstract of manuscript under review
Ethical approval needed/obtained for study: not specified in conference abstract/poster or abstract of manuscript under review
Comments by study authors: not relevant
Miscellaneous outcomes by the review authors: conference abstract; presented at 2019 33rd Annual Meeting of the Associated Professional Sleep Societies, San Antonio, TX; manuscript under review according to authors; Information received from authors concerning study aims: “It aimed to improve well‐being, as measured by various domains including depression, anxiety, perceived stress, self‐esteem, sleep, life satisfaction, and cardiac stress metrics which could be considered correlates or potential mechanisms of resilience. Given that it was a longitudinal design focusing on students, with a 3‐month follow‐up period, we anticipated the participants to experience natural stress associated with being a student and interpret the results as reflecting increased resilience.” corresponding poster and paper of manuscript under review sent by authors
Correspondence: Michael R Goldstein; Department of Psychology, Psychophysiology Research Laboratory; University of Arizona, Tucson, AZ, USA; mgoldstein@email.arizona.edu
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "89 students (age 20.9±3.1 years, 73% female, 86% undergraduate) with general distress complaints were randomly assigned to undergo one of two stress‐management workshops."
Quote (paper abstract; paper under review): "In this study, students were randomized to one of two psychosocial stress‐management interventions."
Judgement comment: based on conference abstract, poster and paper abstract of manuscript under review, insufficient information about random‐sequence generation to permit judgement of ‘Low risk’ or ‘High risk’; verified baseline comparability of groups for sociodemographic characteristics (gender, age, ethnicity, race, student status, GPA; all Ps > 0.377); baseline comparability for outcome variables not specified
Allocation concealment (selection bias) Unclear risk Judgement comment: based on conference abstract, poster and paper abstract of manuscript under review, insufficient information about allocation concealment to permit judgement of ‘Low risk’ or ‘High risk’
Blinding of participants and personnel (performance bias)
Objective outcomes Low risk Judgement comment: based on conference abstract, poster and paper abstract of manuscript under review, blinding of participants and personnel probably not done (face‐to‐face group intervention), but the review authors judge that the outcome is not likely to be influenced by lack of blinding
Blinding of participants and personnel (performance bias)
Subjective outcomes High risk Judgement comment: based on conference abstract, poster and paper abstract of manuscript under review, blinding of participants and personnel probably not done (face‐to‐face group intervention) and the outcome is likely to be influenced by lack of blinding
Blinding of outcome assessment (detection bias)
Objective outcomes Low risk Judgement comment: based on conference abstract, poster and paper abstract of manuscript under review, insufficient information about blinding of outcome assessment, but the review authors judge that the outcome measurement is not likely to be influenced by lack of blinding
Blinding of outcome assessment (detection bias)
Subjective outcomes High risk Judgement: based on conference abstract, poster and paper abstract of manuscript under review, insufficient information about blinding of outcome assessment; but due to potential performance bias (no blinding of participants), the review authors judge that the participants' responses to questionnaires may be affected by the lack of blinding (i.e. knowledge and beliefs about intervention they received)
Incomplete outcome data (attrition bias)
All outcomes High risk Quote: "89 students (age 20.9±3.1 years, 73% female, 86% undergraduate) with general distress complaints were randomly assigned to undergo one of two stress‐management workshops."
Quote (Paper abstract of manuscript under review): "Forty‐five students completed all time‐points and were used for analysis"
Judgement comment: based on conference abstract, poster and paper abstract of manuscript under review, reasons for missing data likely to be related to true outcome with imbalance in missing data between groups: (Pre‐intervention: IG: 1, CG: 2; further withdrawals during workshop: IG: 9, CG: 11; Post‐intervention (further lost to follow‐up): IG: 4, CG: 5; 3‐month follow‐up (further lost to follow‐up): IG: 7, CG: 8); per‐protocol analysis (i.e. only participants who completed workshops) and available‐case analysis (i.e. only participants for whom outcomes were obtained)
Selective reporting (reporting bias) Unclear risk Judgement comment: no study protocol or trial registration available; based on conference abstract, poster and paper abstract of manuscript under review, insufficient information to permit judgement of 'Low risk' or 'High risk'