Table 2.
Mean baseline, 8-week, and difference in concentrations of cardiac biomarkers by diet assignment
| Baseline* | 8-week* | Absolute change from baseline† | %-Difference from Baseline‡ | |
|---|---|---|---|---|
| High sensitivity cardiac troponin I (limit of blank: 0.5), ng/L | ||||
| Control | 1.4 (0.2) | 1.5 (0.2) | 0.1 (−0.2, 0.3) | 6.3 (−10.8, 26.5) |
| Fruits & Vegetables | 2.4 (0.4) | 1.5 (0.2) | −0.9 (−1.4, −0.4) | −37.2 (−49.5, −21.8) |
| DASH (Combination) | 1.2 (0.2) | 0.9 (0.1) | −0.3 (−0.6, −0.1) | −27.1 (−39.5, −12.3) |
| High sensitivity cardiac troponin I (limit of detection: 1.6), ng/L | ||||
| Control | 1.6 (0.2) | 1.7 (0.2) | 0.0 (−0.2, 0.3) | 2.8 (−13.5, 22.2) |
| Fruits & Vegetables | 2.7 (0.4) | 1.8 (0.2) | −0.9 (−1.5, −0.3) | −33.6 (−47.3, −16.4) |
| DASH (Combination) | 1.3 (0.2) | 0.9 (0.1) | −0.4 (−0.6, −0.2) | −30.4 (−42.0, −16.4) |
| N-terminal pro-brain natriuretic peptide, pg/mL | ||||
| Control | 23.1 (2.0) | 24.2 (2.3) | 1.0 (−1.7, 3.8) | 4.5 (−6.7, 17.0) |
| Fruits & Vegetables | 25.0 (2.3) | 20.4 (1.6) | −4.6 (−7.9, −1.2) | −18.3 (−29.0, −6.0) |
| DASH (Combination) | 24.6 (2.0) | 20.5 (2.0) | −4.0 (−7.3, −0.8) | −16.5 (−27.9, −3.2) |
| High sensitivity C-reactive protein, mg/L | ||||
| Control | 1.2 (0.2) | 1.2 (0.1) | −0.0 (−0.2, 0.2) | −0.6 (−17.1, 19.1) |
| Fruits & Vegetables | 1.6 (0.2) | 1.5 (0.2) | −0.0 (−0.3, 0.2) | −2.8 (−19.2, 16.9) |
| DASH (Combination) | 1.7 (0.2) | 1.7 (0.2) | −0.0 (−0.3, 0.2) | −0.8 (−14.7, 15.2) |
DASH represents “Dietary Approaches to Stop Hypertension”
Note there were 108 participants assigned the control diet, 109 participants assigned the fruits & vegetables diet, and 109 participants assigned the DASH diet.
Estimates were derived via weighted mixed effects tobit models. Please reference main text for details.
Exponentiated log-transformed markers or the geometric mean
Difference in exponentiated log-transformed markers (i.e. difference in geometric means)
Exponentiated differences of the change on the log-scale
Conversions: 1 ng/L high sensitivity cardiac troponin I equals 0.001 mg/L; 1 pg/mL of N-terminal pro-brain natriuretic peptide equals 1 ng/L and 0.1182 pmol/L; 1 mg/L high sensitivity C-reactive protein equals 9.5238 nmol/L