Table 4.
Tumor cells sensitive to ferroptosis.
| Cancer type | Therapeutic | Type of evidence | Reference |
|---|---|---|---|
| Hepatocellular carcinoma | Erastin | Cell culture | (Dixon et al., 2012) |
| Sorafenib | Cell culture; Cancer cells from patients | (Lachaier et al., 2014) | |
| Solasonine | Cell culture; Mice xenotransplantation model | (Jin et al., 2020) | |
| Gastric carcinoma | Erastin | Cell culture | (Wang et al., 2016) |
| Sulfasalazine(SAS) | Cell culture | (Okazaki et al., 2018) | |
| Buthionine sulfoximine (BSO) | Cell culture | (Wang et al., 2016) | |
| Ovarian carcinoma | Erastin | Cell culture | (Zhou et al., 2019) |
| Artesunate | Cancer cells from patients | (Greenshields et al., 2017) | |
| Pancreatic carcinoma | Erastin | Cell culture | (Ohman et al., 2016) |
| Artesunate | Cell culture | (Eling et al., 2015) | |
| Sorafenib | Cell culture | (Lachaier et al., 2014) | |
| Piperlongumine | Cell culture | (Yuki et al., 2018) | |
| Breast carcinoma | Erastin | Cell culture | (Ma S. et al., 2017) |
| Siramesine | Cell culture | (Ma S. et al., 2017) | |
| Lapatinib | Cell culture | (Ma S. et al., 2017) | |
| Sulfasalazine(SAS) | Cell culture | (Yu et al., 2019) | |
| Colorectal carcinoma | Erastin | Cell culture; Mice xenotransplantation model |
(Jiang et al., 2015b) |
| Sorafenib | Cell culture | (Lachaier et al., 2014) | |
| Melanoma | BAY 87-2243 | Cell culture; Mice xenotransplantation model |
(Schöckel et al., 2015) |
| Sorafenib | Cell culture; Mice xenotransplantation model |
(Lachaier et al., 2014) | |
| Head and neck cancer | Artesunate | Cell culture; Mice xenotransplantation model |
(Roh et al., 2017) |
| Kidney carcinoma | Erastin | Cell culture; Mice xenotransplantation model |
(Jiang et al., 2015b) |
| Sorafenib | Cell culture | (Lachaier et al., 2014) | |
| Lung carcinoma | Sorafenib | Cell culture | (Lachaier et al., 2014) |
| Glioblastoma | Temozolomide | Cell culture; Mice xenotransplantation model |
(Buccarelli et al., 2018) |
| Lymphoma | Sulfasalazine (SAS) | Cell culture; Mice xenotransplantation model |
(Gout et al., 2001) |
| Retinoblastoma | Sorafenib | Cell culture; Mice xenotransplantation model |
(Louandre et al., 2015; Krainz et al., 2016) |