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. 2020 Jul 2;46(3):989–1002. doi: 10.3892/ijmm.2020.4666

Figure 3.

Figure 3

miR-589-3p mimic partially reversed the effect of TINCR overexpression on the promotion and inhibition of breast cancer cell proliferation and apoptosis, respectively. (A and B) MTT assay was used to detect MCF-7 and MDA-MB-231 cell proliferation. (C-F) Flow cytometry was used to detect MCF-7 and MDA-MB-231 cell apoptosis. All experiments were repeated three times. **P<0.01 vs. pc-Control; ##P<0.01 vs. miR-589-3p mimic control; ΘP<0.05 and ΘΘP<0.01 vs. pc-TINCR; ^^P<0.01 vs. miR-589-3p mimic; ΔΔP<0.001 vs. si-Control; ωωP<0.01 vs. miR-589-3p inhibitor; ρP<0.05, ρρP<0.01 vs. miR-589-3p inhibitor control; ΓΓP<0.01 vs. si-TINCR. miR, microRNA; TINCR, tissue differentiation inducing non-protein coding RNA; si, small interfering.