Figure 4.

miR-589-3p mimic could partially reverse the effect of TINCR overexpression on breast cancer cell migratory and invasive abilities. (A-D) Wound healing assay detected the migratory ability of MCF-7 and MDA-MB-231 cells. (E-H) Invasive ability of MCF-7 and MDA-MB-231 cells detected by Transwell assay. All experiments were repeated three times. ^**P<0.01 vs. pc-Control; ^##P<0.01 vs. miR-589-3p mimic control; ^ΘΘP<0.01 vs. pc-TINCR; ^{^^}P<0.01 vs. miR-589-3p mimic; ^ΔP<0.05 and ^ΔΔP<0.01 vs. si-Control; ^ωωP<0.01 vs. miR-589-3p inhibitor; ^ρρP<0.01 vs. miR-589-3p inhibitor control; ^ΓΓP<0.01 vs. si-TINCR. miR, microRNA; TINCR, tissue differentiation inducing non-protein coding RNA; si, small interfering.