Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 6;46(3):1197–1209. doi: 10.3892/ijmm.2020.4669

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Pecoraro et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Effects of treatments with Doxo alone and in combination with radicicol on MnSOD (A) gene and (B) protein expression of the H9c2 cells. Doxo (1 µM) was administered for 3 and 6 h, and where indicated, radicicol (1 µM) was administered 30 min prior to Doxo. (A) MnSOD mRNA levels were evaluated in the H9c2 cells by RT-qPCR, with the data normalized to the HPRT1 gene, The data are presented as the means ± SD for at least 3 independent experiments, which each performed in triplicate. (B) Superoxide dismutase (MnSOD) levels in the cytosol revealed by flow cytometry of the H9c2 cells. Data are the means ± SEM for the percentages of MnSOD-positive cells, from at least 3 independent experiments, each performed in duplicate. ^*P<0.05 vs. control; (one-way ANOVA and multiple comparisons by Bonferroni's test). Doxo, doxorubicin; Rad, radicicol.