Definitions
Clinical criteria	A fetus or neonate with one or more of the following clinical findings: severe microcephalya with partially collapsed skull; cortical hypoplasia with abnormal gyral patterns; intracranial calcifications located between the cortex and subcortex; macular scarring with focal pigmentary retinal mottling; or congenital contractures of major joints (arthrogryposis) associated with structural brain anomalies; and No positive laboratory test indicating another aetiology that might explain the clinical findings, including congenital infection with a pathogen other than Zika virus (e.g. cytomegalovirus, rubella virus, varicella zoster virus, herpes simplex virus, lymphocytic choriomeningitis virus, Toxoplasma gondii, or Treponema pallidum), or genetic or teratogenic causes of congenital anomalies.
Epidemiologic criteria	Mother with possible exposureb to Zika virus during pregnancy; and No history or suspicion of postnatal mosquito‐borne or bloodborne infection with Zika virus