3. Number of participants and number of participants with data for continuous outcomes (by intervention arm).

	Participants	Total cholesterol	LDL cholesterol	HDL cholesterol	Triglycerides	TG/HDL ratio	Total cholesterol/HDL ratio	LDL/HDL ratio	LP (a)	Insulin sensitivity
Black 1994	133	0	0	0	0	0	0	0	0	0
DART 1989	2033	1855	0	1855	0	0	0	0	0	0
Houtsmuller 1979	102	96	0	0	96	0	0	0	0	96
Ley 2004	176	103	103	103	103	0	103	0	0	103
Moy 2001	267	0	235	235	235	0	0	0	0	0
MRC 1968	393	177	0	0	0	0	0	0	0	0
Oslo Diet‐Heart 1966	412	329	0	0	0	0	0	0	0	0
Oxford Retinopathy 1978	249	58	0	0	0	0	0	0	0	0
Rose corn oil 1965	41	22	0	0	0	0	0	0	0	0
Rose olive 1965	39	24	0	0	0	0	0	0	0	0
Simon 1997	194	72	71	72	71	0	0	0	0	0
STARS 1992	55	50	50	50	50	0	50	50	50	50
Sydney Diet‐Heart 1978	458	458	0	0	458	0	0	0	0	0
Veterans Admin 1969	846	843	0	0	0	0	0	0	0	0
WHI with CVD 2006	2277	0	0	0	0	0	0	0	0	0
WHI 2006	48,835	2832	2832	2832	2832	0	2832	0	2832	2832
WINS 2006	2437	196	0	0	0	0	0	0	0	0
Total Participants	58952	7115	3291	5147	3845	0	2985	50	2882	3081
Percent of participants for this outcome	100%	12%	6%	9%	7%	0%	5%	0.1%	5%	5%

These numbers are the numbers of participants in each study who were available for assessment of outcomes within meta‐analysis (not necessarily the number of participants randomised within the trial).

HDL: high density lipoprotein
LDL: low density lipoprotein
Lp(a): lipoprotein (a)
TG: triglyceride