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. 2020 Jul 22;12:217. doi: 10.3389/fnagi.2020.00217

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Copyright © 2020 Kong, Wang, Wang, Liu, Zhou, Xu, Zhang, Sun and Guan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ZDF rats show AD symptoms. (A–C) Staining rat hippocampus with RAGE antibody (red) and the nuclei with DAPI (blue). (D–F) Staining rat hippocampus with tau antibody (green) and the nuclei with DAPI (blue). (G–I) Staining rat hippocampus with APP antibody (green) and the nuclei with DAPI (blue).