Van Lint 1997.
Methods | Randomized controlled trial | |
Participants | Acute GvHD after allogenic BMT, not responding to 48 hours of 0.5 mg/kg of 6‐MP | |
Interventions | High dose (10mg/kg) 6‐MP vs low dose (2mg/kg) 6‐MP, both reduced every 5 days | |
Outcomes | Clinical response Evolution to aGvHD III‐IV CMV infection actuarial TRM Relapse | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |