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. 2010 Jan 20;2010(1):CD005565. doi: 10.1002/14651858.CD005565.pub2

Van Lint 1997.

Methods Randomized controlled trial
Participants Acute GvHD after allogenic BMT, not responding to 48 hours of 0.5 mg/kg of 6‐MP
Interventions High dose (10mg/kg) 6‐MP vs low dose (2mg/kg) 6‐MP, both reduced every 5 days
Outcomes Clinical response 
 Evolution to aGvHD III‐IV 
 CMV infection 
 actuarial TRM 
 Relapse
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear