Battaglini 2008.

Study characteristics
Methods	Study design: RCT Number randomized: 20, but the numbers assigned to the exercise and control groups not reported Study start and stop dates: not reported Length of intervention: 16 weeks Length of follow‐up: to end of the intervention
Participants	Type cancer: breast cancer Time since cancer diagnosis: not reported Time in active treatment: not reported Inclusion criteria: recently diagnosed women with breast cancer designated to undergo any type of surgery and required to receive either chemotherapy or radiation 35 to 70 years old during the course of the study Eligibility criteria related to interest or ability, or both, to exercise: cardiovascular disease; acute or chronic respiratory disease; acute or chronic bone, joint, or muscular abnormalities that could prevent engagement in regular exercise was exclusionary Exclusion criteria: none Gender: female Current age, mean (SD) years: exercise group: 57.5 (23) years control group: 56.6 (16) years Age at cancer diagnosis: not reported Ethnicity/race: not reported Education level: not reported SES: not reported Employment status: not reported Comorbidities: not reported Past exercise history: not reported On hormone therapy: not reported
Interventions	The number of participants assigned to the exercise intervention: not reported. The exercise intervention included: an individualized exercise program included cardiovascular, resistance, and flexibility training Type exercise (aerobic/anaerobic): aerobic and anaerobic Intensity of the experimental exercise intervention: 40% to 60% of predicted maximum exercise capacity Frequency: twice per week Duration of individual sessions: 60 minutes Duration of exercise program: 16 weeks Total number of exercise sessions: 32 sessions Format: group Facility: facility based Professionally led by an undergraduate or graduate cancer exercise specialist Adherence: not reported The number of participants assigned to the control intervention was not reported and the control intervention was not described Contamination of control group: not reported
Outcomes	Primary outcome: total caloric intake, assessed using 3‐day food diary Other outcomes included: fatigue, assessed using the Revised PFS body composition analysis, assessed using skinfold measurement for the determination of percent body fat fitness assessments included cardiovascular endurance and dynamic muscular endurance Outcomes were measured at baseline; postsurgery; at treatments 1, 2, and 3; and at end of study, but the number of participants at each time point by treatment group was not reported Subgroup analysis: none reported Adverse events: none reported
Notes	Country: US Funding: none reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	The generation of the random sequence was not described
Allocation concealment (selection bias)	Unclear risk	Whether the treatment assignment was concealed from study personnel and participants was not described
Blinding of participants and personnel (performance bias) All outcomes	High risk	Owing to the nature of the intervention, it was not possible to conceal allocation to the intervention from the participants
Blinding of outcome assessment (detection bias) All outcomes	High risk	Allocation to the intervention was not concealed from the study personnel
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	There was no description of missing outcome data or attrition from the trial
Selective reporting (reporting bias)	Unclear risk	Owing to a lack of sufficient description of the outcomes, it is unclear whether there is selective reporting of the outcomes
Other bias	Low risk	The trial appears to be free of other problems that could put it at a high risk of bias