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. 2012 Aug 15;2012(8):CD008465. doi: 10.1002/14651858.CD008465.pub2

Lanctot 2010.

Study characteristics
Methods Study design: RCT
Number randomized: 101; 58 to the exercise group and 43 to the control group
Study start and stop dates: not reported
Length of intervention: 8 weeks
Length of follow‐up: to end of the intervention
Participants Type cancer: breast cancer, Stages I to III
Time since cancer diagnosis: not reported
Time in active treatment: not reported
Inclusion criteria:
  • undergoing chemotherapy


Eligibility criteria related to interest or ability, or both, to exercise:
  • none reported


Exclusion criteria:
  • none reported


Gender: not reported
Current age: not reported
Age at cancer diagnosis: not reported
Ethnicity/race: not reported
Education level: not reported
SES: not reported
Employment status: not reported
Comorbidities: not reported
Past exercise history: not reported
On hormone therapy: not reported
Interventions 58 participants assigned to the exercise intervention, including:
  • yoga postures, visualization, relaxation, meditation, breathing exercises. A video was given for daily home practice


Type exercise (aerobic/anaerobic): unclear
Intensity of the experimental exercise intervention: not reported
Frequency: once per week
Duration of individual sessions: 90 minutes
Duration of exercise program: 8 weeks
Total number of exercise sessions: 8 sessions
Format: not reported
Facility: facility and home
Professionally led by yoga instructors accredited with the Bali method
Adherence: not reported
43 participants assigned to control group, which was not described
Contamination of control group: not reported
Outcomes No primary outcome was identified. QoL outcomes included:
  • global QoL, assessed using the Quality of Life Systematic Inventory and subscales:

    • physical health

    • cognitive functioning

    • affective functioning

    • leisure

    • cancer module

    • familial functioning

    • marital life

  • depression, assessed using the BDI


Outcomes were measured at baseline and at 8 weeks:
  • exercise group: n = 41 at baseline and at 8 weeks

  • control group: n = 32 at baseline and at 8 weeks


Subgroup analysis: none reported
Adverse events: not reported
Notes Country: Canada
Funding: none reported
Published conference abstract
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Generation of allocation sequence was not described
Allocation concealment (selection bias) Unclear risk Whether the treatment assignment was concealed from study personnel and participants was not described
Blinding of participants and personnel (performance bias)
All outcomes High risk Owing to the nature of the intervention, it was not possible to conceal allocation to the intervention from the participants
Blinding of outcome assessment (detection bias)
All outcomes High risk Study personnel and outcome assessors were not masked or blinded to the study interventions
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Insufficient details provided to determine whether there was any attrition
Selective reporting (reporting bias) Unclear risk Insufficient details provided to assess whether there was selective outcome reporting
Other bias Low risk The trial appears to be free of other problems that could put it at a high risk of bias