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. 2020 Jul 7;2020(7):CD008946. doi: 10.1002/14651858.CD008946.pub3

Comparison 6. Denileukin diftitox high versus low dose.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
6.1 Common adverse effects 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.1 Constitutional symptoms 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.2 Grade 3 to 4 constitutional symptoms 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.3 Infections 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.4 Grade 3 to 4 infections 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.5 Gastrointestinal syndromes 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.6 Grade 3 to 4 gastrointestinal syndromes 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.7 CNS syndromes 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.8 Grade 3 to 4 CNS syndromes 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.9 Rash 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.10 Grade 3 to 4 rash 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.11 Vascular leak syndrome 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.12 Grade 3 to 4 vascular leak syndrome 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.13 Thrombotic events 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.14 Grade 3 to 4 thrombotic events 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.15 Cardiopulmonary events 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.16 Grade 3 to 4 cardiopulmonary events 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.17 Acute infusion related events 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.18 Grade 3 to 4 acute infusion related events 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1.19 Grade 3 to 4 laboratory abnormalities 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.2 Complete response 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
6.3 Objective response rate 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only