Fig. 7.

Molecular mapping of cell surface using an AFM tip functionalized with wheat germ agglutinin. In A is shown the AFM image at high resolution from a single cell of the yeast S. cerevisiae, illustrating the presence of 3 bud scars. Panel B & C correspond to the adhesion force maps recorded in PBS buffer between the AFM dendritip functionalized with WGA and the yeast cell surface in the absence (B) or after addition of 200 mM N-acetyl glucosamine (C). White pixels indicate specific adhesion events, whereas black pixels represent non-adhesive events. Corresponding adhesion force histograms (for 1024 force –distance curves) of C and E are shown in panel D and F.