Comparison 2. H. pylori eradication vs control ‐ subgroup analysis according to presence or absence of pre‐neoplastic lesions at baseline.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
2.1 Incidence of gastric cancer according to presence or absence of pre‐neoplastic lesions at baseline	7	8307	Risk Ratio (M‐H, Random, 95% CI)	0.64 [0.43, 0.96]
2.1.1 Patients with precancerous lesions	4	3425	Risk Ratio (M‐H, Random, 95% CI)	0.86 [0.47, 1.59]
2.1.2 Patients without precancerous lesions	2	1812	Risk Ratio (M‐H, Random, 95% CI)	0.42 [0.02, 7.69]
2.1.3 Mixed patients with and without precancerous lesions or ulcer (can't separate)	3	3070	Risk Ratio (M‐H, Random, 95% CI)	0.42 [0.22, 0.78]