1. Overview of study population.
| Study ID | Intervention | [n] screened | [n] randomised | [n] ITT | [n] finishing study | [%] of randomised participants finishing study | comments |
| Barth 2005 | Intervention (I): Resource‐orientated Psychotherapy Control (C): Usual Care |
Total: 1709 | I: 27 C: 32 Total: 59 |
I: 27 C: 32 Total: 59 |
I: 27 C: 28 Total: 55 |
I: 100% C: 87.5% Total: 93.2% |
|
| Brown 1993 | Intervention (I): Behavior Therapy Control (C): Person‐centered Therapy |
Total: 107 | I: NR C: NR Total: 54 |
I: NR C: NR Total: NR |
I: 20 C: 20 Total: 40 |
I: ? C: ? Total: 74.1% |
|
| CREATE 2007 | Intervention 1 (I1): Interpersonal Psychotherapy Intervention 2 (I2): Citalopram Control 1 (C1): Clinical management Control 2 (C2): Placebo |
Total: 1897 | I1: 142 I2: 142 C1: 142 C2: 142 Total: 284 |
I1: 142 I2: 142 C1: 142 C2: 142 Total: 284 |
I1: 118 I2: 124 C1: 112 C2: 106 Total: 230 |
I1: 83.1% I2: 87.3% C1: 78.9% C2: 74.6% Total: 81.0% |
2 X 2 factorial trial |
| Doering 2007 | Intervention (I): Cognitive Behavioral Therapy Control (C): Usual care |
Total: 117 | I: NR C: NR Total: NR |
I: NR C: NR Total: NR |
I: 7 C: 8 Total: 15 |
I: ? C: ? Total: ? |
|
| ENRICHD 2003 | Intervention (I): Cognitive Behavior Therapy Control (C): Usual Care |
Total: 33780 | I: 1238 C: 1243 Total: 2481 |
I: 1238 C: 1243 Total: 2481 |
I: 983 C: 985 Total: 1968 |
I: 79.4% C: 79.2% Total: 79.3% |
|
| Fang 2003 | Intervention (I): Health Education and Psychological Intervention Control (C): Usual care |
Total: ? | I: 27 C: 30 Total: 57 |
I: C: Total: |
I: C: Total: |
I: C: Total: |
|
| Freedland 2009 | Intervention 1 (I1): Cognitive Behavior Therapy Intervention 2 (I2): Supportive Stress Management Control (C): Usual Care for depression |
Total: 2955 | I1: 41 I2: 42 C1: 40 Total: 123 |
I1: 41 I2: 42 C1: 40 Total: 123 |
I1: 40 I2: 33 C1: ? Total: ? |
I1: 98% I2: 79% C1: ? Total: ? |
|
| Freeman 1986 | Intervention (I): Alprazolam Control (C): Placebo |
Total: 459 | I: 54 C: 53 Total: 107 |
I: NR C: NR Total: NR |
I: 32 C: 28 Total: 60 |
I: 59.3% C: 52.8% Total: 56.1% |
|
| Li 2005 | Intervention (I): St. John's Wort extract Control (C): Placebo |
Total: ? | I: ? C: ? Total: 87 |
I: ? C: ? Total: ? |
I: 43 C: 39 Total: 82 |
I: ? C: ? Total: 94.3% |
|
| Liu 1999 | Intervention (I): Fluoxetine Control (C): Placebo |
Total: ? | I: ? C: ? Total: ? |
I: ? C: ? Total: ? |
I: 31 C: 37 Total: ? |
I: ? C: ? Total: ? |
|
| McFarlane 2001 | Intervention (I): Sertraline Control (C): Placebo |
Total: 238 | I: 18 C: 20 Total: 38 |
I: NR C: NR Total: NR |
I: 12 C: 15 Total: 27 |
I: 66.7% C: 75.0% Total: 71.1% |
|
| McLaughlin 2005 | Intervention (I1): Telephone counseling Control (C): Usual care |
Total: 700 | I: 53 C: 47 Total: 100 |
I: NR C: NR Total: NR |
I: 45 C: 34 Total: 79 |
I: 84.9% C: 72.3% Total: 79% |
|
| MIND‐IT 2007 | Intervention (I): Mirtazapine Control (C): Placebo |
Total: 2177 | I: 47 C: 44 Total: 91 |
I: 47 C: 44 Total: 91 |
I: 22 C: 18 Total: 40 |
I: 46.8% C: 40.9% Total: 44.0% |
|
| Roose 1998 | Intervention 1 (I1): Paroxetine Intervention 2 (I2): Nortriptyline |
Total: NR | I1: 41 I2: 40 Total: 81 |
I1: 41 I2: 40 Total: 81 |
I1: 37 I2: 30 Total: 67 |
I1: 90.2% I2: 75.0% Total: 82.7% |
|
| SADHART 2002 | Intervention (I): Sertraline Control (C): Placebo |
Total: 11546 | I: 186 C: 183 Total: 369 |
I: 186 C: 183 Total: 169 |
I: 133 C: 137 Total: 270 |
I: 71.5% C: 74.9% Total: 73.1% |
|
| Strik 2000 | Intervention (I): Fluoxetine Control (C): Placebo |
Total: 556 | I: 27 C: 27 Total: 54 |
I: 27 C: 27 Total: 54 |
I: 22 C: 18 Total: 40 |
I: 81.5% C: 66.7% Total: 74.1% |
ITT = intention‐to‐treat; NR = not reported; ? = unclear