UPBEAT 2007.

Trial name or title	Understanding prognostic benefits of exercise and antidepressant therapy (UPBEAT) NCT00302068
Methods	RCT design: 3‐armed parallel‐group trial Target number of participants: 200 Length of follow‐up: 12 months
Participants	Location: USA Inclusion criteria: Patients with coronary heart disease (CHD) and depressive symptoms (Beck Depression Inventory (BDI‐II) score 9 or greater)
Interventions	Treatment: Aerobic exercise Active comparator: Sertraline Control: Placebo
Outcomes	Primary outcome: Hamilton Rating Scale for Depression (HAM‐D)
Starting date	July 2006
Contact information	James A. Blumenthal, PhD: blume003@mc.duke.edu Andrew Sherwood, PhD: sherw002@mc.duke.edu
Notes	Funding: National Heart, Lung, and Blood Institute, USA