Li 2011b.

Study characteristics
Methods	Randomization using a randomization table
Participants	28 women with CSP
Interventions	Systemic MTX intravenously 50 mg/m2 of body surface area (size of sac/mass: 129.6 ± 96.7 cm3; 13 cases, age:33.2 ± 4.5y) treatment vs UACE plus MTX 40 mg and gelatin sponge particles (size of sac/mass: 161.1 ± 102.1 cm3; 15 cases, age:34.2 ± 5.5y) suction curettage performed when β‐hCG decreased to < 50 mIU/mL in systemic MTX group suction curettage performed after 24 hours in UACE group
Outcomes	Primary outcomes: success after initial treatment complications: emergency hysterectomy, tamponade with iodoform gauze, a second UAE Secondary outcomes: adverse effects (including mild increase in liver enzymes, mild vomiting, moderate abdominal or pelvic pain) blood loss hospital stay
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "By using a randomization table."
Allocation concealment (selection bias)	Unclear risk	No data available for this specific type of bias.
Blinding of participants and personnel (performance bias) All outcomes	High risk	No data available for this specific type of bias, and blinding was not possible with this methodology.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No data available for this specific type of bias.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No missing outcome data.
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement.
Other bias	Unclear risk	Insufficient information to assess whether an important risk of bias existed.