Table 3.
Acute hematologic toxicity
| Toxicity | PBMS group n (%) | Control group n (%) | p |
|---|---|---|---|
| HT2+ | 41 (50.0) | 57 (69.5) | 0.02a |
| Leukopenia | |||
| Grade 0 | 13 (15.9) | 8 (9.8) | < 0.01a |
| Grade 1 | 32 (39.0) | 22 (26.8) | |
| Grade 2 | 35 (42.7) | 37 (45.1) | |
| Grade 3 | 2 (2.4) | 15 (18.3) | |
| Grade 4 | 0 | 0 | |
| Neutropenia | |||
| Grade 0 | 51 (62.2) | 35 (42.7) | <0.01a |
| Grade 1 | 20 (24.4) | 11 (13.4) | |
| Grade 2 | 9 (11.0) | 30 (36.6) | |
| Grade 3 | 2 (2.4) | 5 (6.1) | |
| Grade 4 | 0 | 1 (1.2) | |
| Anemia | |||
| Grade 0 | 68 (82.9) | 52 (63.4) | 0.02a |
| Grade 1 | 10 (12.2) | 19 (23.2) | |
| Grade 2 | 4 (4.9) | 11 (13.4) | |
| Grade 3 | 0 | 0 | |
| Grade 4 | 0 | 0 | |
| Thrombocytopenia | |||
| Grade 0 | 81 (98.8) | 68 (82.9) | < 0.01a |
| Grade 1 | 1 (1.2) | 10 (12.2) | |
| Grade 2 | 0 | 2 (2.4) | |
| Grade 3 | 0 | 1 (1.2) | |
| Grade 4 | 0 | 1 (1.2) | |
| GT2+ | 29 (35.4) | 31 (37.8) | 0.75 |
| Grade 0 | 14 (17.1) | 17 (20.7) | 0.68 |
| Grade 1 | 39 (47.6) | 34 (41.5) | |
| Grade 2 | 29 (35.4) | 31 (37.8) | |
| Grade 3 | 0 | 0 | |
| Grade 4 | 0 | 0 | |
Abbreviation: HT2+ hematologic toxicity of grade ≥ 2, GT2+ gastrointestinal toxicity of grade ≥ 2
aStatistically significant