Table 3.
Logistic regression analysis of factors influencing HbA1c response (fall of of ≥5 mmol/mol (0.5%)) following commencement of flash monitoring
All individuals with type 1 diabetes (n=1741) | Individuals with baseline HbA1c ≥53 mmol/mol (7.0%) (n=1428) | |||||
OR | 95% CI | P value | OR | 95% CI | P value | |
HbA1c below 65 mmol/mol (8.1%) | 0.25 | 0.20 to 0.31 | <0.001 | 0.35 | 0.28 to 0.43 | <0.001 |
Early flash monitoring start (first prescription in February or March 2018) | 1.46 | 1.18 to 1.81 | <0.001 | 1.38 | 1.10 to 1.74 | 0.005 |
Age (per year increment) | 0.162 | 0.011 to 2.320 | 0.180 | 0.986 | 0.977 to 0.994 | 0.001 |
Age at diagnosis (per year increment) | 6.14 | 0.43 to 88.64 | 0.182 | 1.01 | 1.00 to 1.02 | 0.091 |
Fewer than two sensors per month collected | 0.62 | 0.45 to 0.84 | 0.002 | 0.63 | 0.45 to 0.86 | 0.005 |
SIMD 1 (most deprived quintile) | 0.60 | 0.40 to 0.88 | 0.010 | 0.60 | 0.40 to 0.90 | 0.014 |
Male | 1.31 | 1.06 to 1.62 | 0.013 | 1.29 | 1.03 to 1.62 | 0.026 |
DAFNE | 1.15 | 0.93 to 1.44 | 0.202 | 1.14 | 0.90 to 1.43 | 0.277 |
CSII | 0.90 | 0.70 to 1.16 | 0.416 | 0.93 | 0.71 to 1.22 | 0.615 |
Analysis presented for the complete cohort and also when limited to those with HbA1c >53 mmol/mol (7.0%) at baseline.
CSII, continuous subcutaneous insulin infusion; DAFNE, Dose Adjustment for Normal Eating; HbA1c, hemoglobin A1c; SIMD, Scottish Index of Multiple Deprivation.