Table 4.
Multiple logistic regression model to validate the independent association of adequate gestational weight gain (GWG) and other confounding factors for term preeclampsia)
Multiple logistic regression for term preeclampsia (≥37 weeks) | ||||
Coefficient | OR | 95% CI | P value | |
Optimal GWG (Yes/no) | −0.30 | 0.73 | 0.59 to 0.92 | 0.007 |
Smoking | −0.29 | 0.74 | 0.56 to 0.98 | 0.04 |
Maternal BMI (increment of 5 kg/m²) |
0.06 | 1.06 | 1.05 to 1.07 | <0.0001 |
Gestational diabetes mellitus | −0.058 | 0.94 | 0.74 to 1.18 | 0.61 |
Chronic hypertension | 1.51 | 4.5 | 3.3 to 6.2 | <0.0001 |
Maternal age (increment of 5 years of age) |
0.03 | 1.03 | 1.02 to 1.05 | <0.0001 |
Primiparity | 1.07 | 2.9 | 2.45 to 3.48 | <0.0001 |
Optimal GWG and smoking (negative coefficient) have a similar protective effect of 0.74. Primiparity, maternal body mass index (BMI), chronic hypertension and maternal ages increase the risk. Controlling for all the other factors, maternal prepregnancy BMI is still an independent factor (coefficient 0.06, increment of 6% per increment of 5 kg/m²).