Characteristic	Derosa 2004	Derosa 2006a	Derosa 2006b
	I1: rosiglitazone 4 mg + glimepiride 4 mg C1: pioglitazone 15 mg + glimepiride 4 mg	I1: rosiglitazone 4 mg + metformin 3000 mg C1: pioglitazone 15 mg + metformin 3000mg	I1: rosiglitazone 4 mg + metformin 1500 mg C1: glimepiride 2 mg + metformin 1500 mg
[n] of participants who died	I1: 0 C1: 0	?	I1: 0 C1:0
[%] adverse events	I1: 11.9 (5/42) C1: 6.7 ( 3/45)	I1: 10.4 (5/48) C1: 8.3 (4/48)	I: 12.5 (6/48) C1:8.5 (4/47)
[%] serious adverse events	I1: 0 C1: 0	?	?
[%] drop‐outs due to adverse events	I1: 0 C1: 0	?	?
[%] oedema	?	?	?
haemoglobin [g/dl]	?	?	?
body weight [kg]	?	?	I1: ? C1: ?
body mass index (BMI) [kg/m2]	I1: +1.5 C1: +1.2	I1: ‐ 0.4 C1: ‐0.3	I1: ‐2.1 C1: ‐1.6
[%] hypoglycaemic episodes	?	?	?
[%] severe hypoglycaemic episodes	?	?	?
Notes	BMI change date calculated	BMI change data calculated	BMI change date calculated
Footnotes ? = unclear; I = intervention; C = control