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. 2020 Jul 7;2020(7):CD012362. doi: 10.1002/14651858.CD012362.pub3

Comparison 1. Supine midline head position versus any other supine head position.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Intraventricular haemorrhage, any grade 3 290 Risk Ratio (M‐H, Fixed, 95% CI) 1.11 [0.78, 1.56]
1.1.1 Supine midline head position with the bed at 0° versus supine head rotated 90° with the bed at 0° 2 110 Risk Ratio (M‐H, Fixed, 95% CI) 1.14 [0.55, 2.35]
1.1.2 Supine midline head position with the bed tilted ≥ 30° versus supine head rotated 90° with the bed at 0° 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 1.10 [0.74, 1.62]
1.2 Intraventricular haemorrhage, grade 3 to 4 3 290 Risk Ratio (M‐H, Fixed, 95% CI) 0.71 [0.37, 1.33]
1.2.1 Supine midline head position with the bed at 0° versus supine head rotated 90° with the bed at 0° 2 110 Risk Ratio (M‐H, Fixed, 95% CI) 1.57 [0.28, 8.98]
1.2.2 Supine midline head position with the bed at ≥30° versus supine head rotated 90° with the bed at 0° 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 0.61 [0.31, 1.22]
1.3 Neonatal mortality (within 28 days of life) 3 290 Risk Ratio (M‐H, Fixed, 95% CI) 0.49 [0.25, 0.93]
1.3.1 Supine midline head position with the bed at 0° versus supine head rotated 90° with the bed at 0° 2 110 Risk Ratio (M‐H, Fixed, 95% CI) 0.52 [0.16, 1.65]
1.3.2 Supine midline head position with the bed tilted ≥ 30° versus supine head rotated 90° with the bed at 0° 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 0.47 [0.21, 1.03]
1.4 Mortality during initial hospitalization 3 290 Risk Ratio (M‐H, Fixed, 95% CI) 0.50 [0.28, 0.90]
1.4.1 Supine midline head position with the bed at 0° versus supine head rotated 90° with the bed at 0° 2 110 Risk Ratio (M‐H, Fixed, 95% CI) 0.52 [0.16, 1.65]
1.4.2 Supine midline head position with the bed tilted ≥ 30° versus supine head rotated 90° with the bed at 0° 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 0.50 [0.26, 0.97]
1.5 Cystic periventricular leukomalacia 2 228 Risk Ratio (M‐H, Fixed, 95% CI) 3.25 [0.14, 76.01]
1.5.1 Supine midline head position with the bed at 0° versus supine head rotated 90° with the bed at 0° 1 48 Risk Ratio (M‐H, Fixed, 95% CI) 3.25 [0.14, 76.01]
1.5.2 Supine midline head position with the bed at ≥30° versus supine head rotated 90° with the bed at 0° 1 180 Risk Ratio (M‐H, Fixed, 95% CI) Not estimable
1.6 Retinopathy of prematurity, any stage 1 42 Risk Ratio (M‐H, Fixed, 95% CI) 2.27 [0.85, 6.11]
1.7 Retinopathy of prematurity, ≥ stage 3 2 222 Risk Ratio (M‐H, Fixed, 95% CI) 0.90 [0.41, 1.97]
1.7.1 Supine midline head position with the bed at 0° versus supine head rotated 90° with the bed at 0° 1 42 Risk Ratio (M‐H, Fixed, 95% CI) 2.73 [0.31, 24.14]
1.7.2 Supine midline head position with the bed tilted ≥ 30° versus supine head rotated 90° with the bed at 0° 1 180 Risk Ratio (M‐H, Fixed, 95% CI) 0.73 [0.31, 1.72]