Table 2.
Summary table illustrating the distribution of BIN1 exons and isoforms in different cell types in CNS
| DLPFC - Bulk RNA-seq | Neuron – Immunofluorescence Exon Specific Antibody | Astrocyte – Immunofluorescence Exon Specific Antibody | Microglia - Purified Microglia RNA-seq | Microglia – Immunofluorescence Exon Specific Antibody | |
|---|---|---|---|---|---|
| Isoform 1 | Yes | exon 7 | exon 7 | No | No |
| Isoform 2 | Yes | exon 7 | exon 7 | No | No |
| Isoform 3 | Yes | exon 7 | exon 7 | No | No |
| Isoform 4 | No | No | No | No | No |
| Isoform 5 | Yes | exon 11, 13 | exon 11, 13 | No | No |
| Isoform 6 | Yes | exon 11, 13 | exon 11, 13 | Yes | exon 11, 13 |
| Isoform 7 | Yes | exon 16 | exon 16 | No | No |
| Isoform 8 | No | No | No | No | No |
| Isoform 9 | Yes | data N/A | data N/A | Yes | data N/A |
| Isoform 10 | Yes | data N/A | data N/A | Yes | data N/A |
| Isoform 12 | Yes | data N/A | data N/A | Yes | data N/A |