Date	Event	Description
10 June 2020	Amended	Clarification statement added from Alan Smyth, Co‐ordinating Editor on 10 June 2020: This review was found by the Cochrane Funding Arbiters, post‐publication, to be noncompliant with the Cochrane conflict of interest policy, which includes the relevant parts of the Cochrane Commercial Sponsorship Policy. However, the Editorial Board of the Cochrane Cystic Fibrosis and Genetic Disorders Review Group believe that it is important that this empty review remains published on the Cochrane Library to reflect the current lack of evidence. This will enable researchers in countries who do not yet have funding to participate in an upcoming trial, to use this review in their application to highlight the evidence gap and to increase the likelihood of success of any funding application. The Cochrane Funding Arbiters have therefore agreed to allow this empty review to remain available for a limited time. The review will be updated by June 2022; the author team of the future update will be compliant with Cochrane policy.
10 June 2020	New search has been performed	A search of the Cystic Fibrosis and Genetic Disorders Review Group's Cystic Fibrosis Trials Register identified four additional references. Two references were to a study previously listed as 'Awaiting assessment' (Olivier 2017). We have not yet been able to include this study as we need data for the participants relevant to this review who are a subset of the whole cohort. Data have been requested and will be included when received. The second study (two references) is a comparison of people with cystic fibrosis and healthy controls; this study has been excluded as all the participants with cystic fibrosis received the same treatment (Martiniano 2017). A search of online trials registries identified two studies. One study was an observational study and not even listed as excluded in this review; the second study has been excluded since all participants received the same intervention and no comparison is possible (ABATE).
10 June 2020	New citation required but conclusions have not changed	No data have been added at this update, therefore our conclusions remain the same.