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. 2020 Jul 10;2020(7):CD013600. doi: 10.1002/14651858.CD013600.pub2

5. Serious adverse events .

Study Number of participants Serious adverse events
Ahn 2020 2 0
Duan 2020 10 (convalescent plasma group) 0
Jin 2020
  6
 
  0
Joyner 2020
 
  5000
 
  Within 4 hours after transfusion
  • 15 dead (4 potentially, probably, or definitely related)

  • 7 TACO (7 potentially, probably, or definitely related)

  • 11 TRALI (11 potentially, probably, or definitely related)

  • 3 severe allergic reaction (3 potentially, probably, or definitely related)

Li 2020
  52 (convalescent plasma group)
  1 possible severe transfusion‐associated dyspnoea (patient had "shortness of breath, cyanosis, and severe dyspnoea within 6 hours of transfusion. The  participant was given dexamethasone, aminophylline, and other supportive care immediately and gradually improved after 2 hours)."   
 
 
Liu 2020
  39 (convalescent plasma group)
  0
 
 
Pei 2020 3 1 (anaphylactic shock)
Perotti 2020
  46
  3
  • anaphylaxis/hypersensitivity (relation possible)

  • TRALI (relation possible)

  • subsegmental pulmonary embolism (relation unlikely/excluded)

Salazar 2020
  25 
  0
 
 
Tan 2020 1 0
Ye 2020 6 0
Zeng 2020
  6 (convalescent plasma group)
  0
 
Zhang 2020a 4 0
Zhang 2020b 1 0
TACO: transfusion‐associated circulatory overload; TRALI: transfusion‐related acute lung injury