Table 1.
Socio-demographics, clinical characteristics and metabolic indictors between patients with and without suicide attempts
| Variable | MDD without suicide attempt (n = 612) | MDD with suicide attempt (n = 128) | F/X2 | P value | ||
|---|---|---|---|---|---|---|
| Age, mean (SD), y | 22.68 | 4.09 | 22.98 | 3.765 | 0.610 | 0.435 |
| Course of disease, mean (SD), m | 4.58 | 2.99 | 5.54 | 3.85 | 9.710 | 0.002** |
| Gender | ||||||
| Male, n (%) | 236 | 38.6 | 51 | 39.8 | ||
| Female, n (%) | 376 | 61.4 | 77 | 60.2 | ||
| Cultural degree | ||||||
| Junior high school education level, n (%) | 29 | 4.8 | 13 | 10.2 | ||
| Senior high school education level, n (%) | 300 | 49.0 | 55 | 43.0 | ||
| University education level, n (%) | 240 | 39.2 | 50 | 39.0 | ||
| Postgraduate education level, n (%) | 43 | 7.0 | 10 | 7.8 | ||
| Marital status | ||||||
| Single | 384 | 62.7 | 86 | 67.2 | ||
| Married | 228 | 37.3 | 42 | 32.8 | ||
| HAMD, mean (SD) | 29.71 | 2.84 | 32.08 | 2.75 | 74.600 | < 0.001 *** |
| HAMA, mean (SD) | 20.03 | 3.10 | 23.20 | 3.47 | 105.711 | < 0.001 *** |
| Obvious anxiety (HAMA ≥21), n (%) | 270 | 44.1 | 102 | 79.7 | 740 | < 0.001 *** |
| Psychotic symptoms (PANSS ≥15), n (%) | 43 | 7.02 | 24 | 18.75 | 6.643 | 0.012* |
| BMI, mean (SD), kg/m2 | 24.31 | 1.87 | 24.14 | 2.75 | 0.694 | 0.405 |
| SBP, mean (SD), mmHg | 111.82 | 9.19 | 119.42 | 12.57 | 62.909 | < 0.001*** |
| DBP, mean (SD), mmHg | 72.98 | 5.81 | 76.63 | 7.01 | 38.651 | < 0.001*** |
| FBG, mean (SD), mmol/L | 5.32 | 0.61 | 5.61 | 0.70 | 23.145 | < 0.001*** |
| Increase (FBG > 6.10 mmol/L), n (%) | 66 | 10.8 | 29 | 22.7 | ||
| Normal (3.90–6.10 mmol/L), n (%) | 546 | 89.2 | 99 | 77.3 | ||
| TC, mean (SD), mmol/L | 5.00 | 1.07 | 5.80 | 1.14 | 57.461 | < 0.001*** |
| Increase (TC ≥ 5.17 mmol/L), n (%) | 255 | 41.6 | 83 | 64.8 | ||
| Normal (TC < 5.17 mmol/L), n (%) | 357 | 58.4 | 45 | 35.2 | ||
| HDL-C, mean (SD), mmol/L | 1.25 | 0.28 | 1.12 | 0.31 | 20.920 | < 0.001*** |
| Decrease (HDL-C < 1.04 mmol/L), n (%) | 147 | 24.0 | 55 | 43.0 | ||
| Normal (1.04–2.07 mmol/L), n (%) | 465 | 76.0 | 73 | 57.0 | ||
| LDL-C, mean (SD), mmol/L | 2.84 | 0.86 | 3.17 | 1.01 | 14.378 | < 0.001*** |
| Increase (LDL-C ≥ 3.10 mmol/L), n (%) | 222 | 36.3 | 70 | 54.7 | ||
| Normal (LDL-C < 3.10 mmol/L), n (%) | 390 | 63.7 | 58 | 45.3 | ||
| TG, mean (SD), mmol/L | 2.12 | 0.97 | 2.25 | 1.05 | 1.756 | 0.185 |
| Increase (TG > 1.69 mmol/L), n (%) | 368 | 60.0 | 79 | 61.7 | ||
| Normal (0.56–1.69 mmol/L), n (%) | 244 | 40.0 | 49 | 38.3 | ||
Note: MDD major depressive disorder, HAMD Hamilton depression rating scale, HAMA Hamilton anxiety rating scale, PANSS The Positive and Negative Syndrome Scale, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride. *p < 0.05; **p < 0.01; ***p < 0.001